ALF
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Official Full Name
general transcription factor IIA, 1-like -
Overview
The assembly and stability of the RNA polymerase II transcription pre-initiation complex on a eukaryotic core promoter involve the effects of TFIIA on the interaction between TATA-binding protein (TBP) and DNA. This gene encodes a germ cell-specific counterpart of the large (alpha/beta) subunit of general transcription factor TFIIA that is able to stabilize the binding of TBP to DNA and may be uniquely important to testis biology. Alternative splicing for this locus has been observed and two variants, encoding distinct isoforms, have been identified. Co-transcription of this gene and the neighboring upstream gene generates a rare transcript (SALF), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. -
Synonyms
Limulus Antilipopolysaccharide Factor;LALF
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Involved Pathway
ALF involved in several pathways and played different roles in them. We selected most pathways ALF participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ALF were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
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Protein Function
ALF has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by ALF itself. We selected most functions ALF had, and list some proteins which have the same functions with ALF. You can find most of the proteins on our site.
| Function | Related Protein |
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Interacting Protein
ALF has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ALF here. Most of them are supplied by our site. Hope this information will be useful for your research of ALF.
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