ALDH3A2
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Official Full Name
aldehyde dehydrogenase 3 family, member A2 -
Overview
Aldehyde dehydrogenase isozymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. This gene product catalyzes the oxidation of long-chain aliphatic aldehydes to fatty acid. Mutations in the gene cause Sjogren-Larsson syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. -
Synonyms
ALDH3A2;aldehyde dehydrogenase 3 family, member A2;ALDH10, SLS;fatty aldehyde dehydrogenase;FALDH;aldehyde dehydrogenase 10;microsomal aldehyde dehydrogenase;aldehyde dehydrogenase family 3 member A2;SLS;ALDH10;FLJ20851;DKFZp686E23276
Recombinant Proteins
- Chicken
- Mouse
- Cynomolgus
- Human
- Rat
- Mus musculus
- Mammalian Cells
- Wheat Germ
- E.coli
- HEK293
- In Vitro Cell Free System
- His
- GST
- Non
- Flag
- Avi&His&Fc
- Myc&DDK
- His&Fc&Avi
Involved Pathway
ALDH3A2 involved in several pathways and played different roles in them. We selected most pathways ALDH3A2 participated on our site, such as Glycolysis / Gluconeogenesis,Pentose and glucuronate interconversions,Ascorbate and aldarate metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with ALDH3A2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Ascorbate and aldarate metabolism | MIOX,UGT1A6,UGT2A2,ALDH2.1,UGT1A6B,UGT1A9,UGT1A4,ALDH3A2A,GKUP,UGT2B7 |
| Pentose and glucuronate interconversions | ALDH2.2,GKUP,UGP2B,UGT2B7,UGT2B15,UGT1A6,UGT1A6B,AKR1A1B,UGT1AB,DCXR |
| Pyruvate metabolism | ACACB,PDHA2,SLC16A1,PC,ACSS2,LDHA,SLC16A8,PKMB,ACAT1,ALDH9A1A.1 |
| Glycolysis / Gluconeogenesis | GAPDH,PFKMA,LDHAL6A,PGM1,ADH2-2,FBP1B,PGAM2,PKLR,HK3,ALDH3B1 |
| Metabolic pathways | GUK1B,HSD17B4,HSD17B10,ADH6,HMBSB,EHHADH,TDO2B,CTPS1A,NME6,CYP19A1B |
| Glycerolipid metabolism | ALDH2.2,GLYCTK,AKR1B10,AGPAT5,ALDH2.1,AGPAT3,PNPLA3,PPAP2A,MOGAT2,PPAP2CB |
| Arginine and proline metabolism | ARG1,GOT2B,ALDH9A1B,CKB,ALDH2.2,SMOX,LAP3,PRODH2,ADC,P4HA1A |
| beta-Alanine metabolism | CNDP1,HADHA,UPB1,ALDH3B2,GAD1B,HIBCH,SRM,ALDH2.1,CNDP2,HADHAA |
| Fatty acid degradation | CPT1C,ALDH9A1,GCDH,CYP4A12A,CYP4A10,GCDHB,CPT2,CYP4A11,ACSL3B,ALDH7A1 |
Protein Function
ALDH3A2 has several biochemical functions, for example, 3-chloroallyl aldehyde dehydrogenase activity,aldehyde dehydrogenase (NAD) activity,aldehyde dehydrogenase [NAD(P)+] activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ALDH3A2 itself. We selected most functions ALDH3A2 had, and list some proteins which have the same functions with ALDH3A2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| aldehyde dehydrogenase [NAD(P)+] activity | ALDH3B1,ALDH3A2B,ALDH2,ALDH3A2A,ALDH1A3,ALDH3A1,ALDH3B2 |
| aldehyde dehydrogenase (NAD) activity | ALDH1A3,ALDH7A1,ALDH2,ALDH9A1A.1,ALDH3A2A,ALDH4A1,ALDH16A1,ALDH9A1B,ALDH8A1,ALDH1L2 |
| 3-chloroallyl aldehyde dehydrogenase activity | ALDH2.1,ALDH3A2A,ALDH3B2,ALDH3A1,ALDH1A1,ALDH9A1,Aldh1a7,ALDH3A2B,ALDH3B1 |
Interacting Protein
ALDH3A2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ALDH3A2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ALDH3A2.
Stag2;USP50;Mad2l2;p29991-pro_0000037946;midostaurin;AIM2;PPP6R2;GABARAP;1C;MME;CAPZA2;GABARAPL2;Tubg1;Smn1;KPNB1;Prkci;Atp7a;ATL3;Tnpo1
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