AKAP6
-
Official Full Name
A kinase (PRKA) anchor protein 6 -
Overview
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of;binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within;the cell. This gene encodes a member of the AKAP family. The encoded protein is highly expressed in various brain;regions and cardiac and skeletal muscle. It is specifically localized to the sarcoplasmic reticulum and nuclear;membrane, and is involved in anchoring PKA to the nuclear membrane or sarcoplasmic reticulum. -
Synonyms
AKAP6;A kinase (PRKA) anchor protein 6;A-kinase anchor protein 6;ADAP6;AKAP100;KIAA0311;mAKAP;PRKA6;protein kinase A anchoring protein 6;AKAP-6;AKAP 100;A-kinase anchor protein 100 kDa;protein kinase A-anchoring protein 6;ADAP100;MGC165020
Recombinant Proteins
- Human
- Rat
- E.coli
- Wheat Germ
- Mammalian Cell
- HEK293
- GST
- His
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| AKAP6-9523H | Recombinant Human AKAP6, GST-tagged | E.coli | Human | GST | 1-350a.a. | |
| AKAP6-32H | Recombinant Human AKAP6 protein, GST-tagged | Wheat Germ | Human | GST | 2221-2318 a.a. |
|
| AKAP6-592R | Recombinant Rat AKAP6 Protein | Mammalian Cell | Rat | His |
|
|
| AKAP6-715H | Recombinant Human AKAP6 | Mammalian Cell | Human | His |
|
|
| AKAP6-2452H | Recombinant Human AKAP6 Protein, His (Fc)-Avi-tagged | HEK293 | Human | His&Fc&Avi |
|
|
| AKAP6-2452H-B | Recombinant Human AKAP6 Protein Pre-coupled Magnetic Beads | HEK293 | Human |
|
||
| AKAP6-248R | Recombinant Rat AKAP6 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
|
|
| AKAP6-248R-B | Recombinant Rat AKAP6 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
|
Involved Pathway
AKAP6 involved in several pathways and played different roles in them. We selected most pathways AKAP6 participated on our site, such as G Protein Signaling Pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with AKAP6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| G Protein Signaling Pathways | AKAP1,GNB3B,AKAP5,GNG13B,AKAP1B,AKAP12,Akap3,GNGT2A,Akap2,ARHGEF1A |
Protein Function
AKAP6 has several biochemical functions, for example, adenylate cyclase binding,ion channel binding,protein anchor. Some of the functions are cooperated with other proteins, some of the functions could acted by AKAP6 itself. We selected most functions AKAP6 had, and list some proteins which have the same functions with AKAP6. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein anchor | SLC4A1,CIB1,SUN5,SUN3,PDCD6,ALG14,NUP153,MYH9,SUN1,RAPSN |
| ion channel binding | KCNH1,CALM3,ARRB1,PANX1,AP2M1,HOMER1,NEDD4L,CAV1,KCNE4,PACS1 |
| protein kinase A binding | RARA,AKAP12,AKAP7,AKAP12B,LRRK2,RPS3,AKAP5,DACT2,MYRIP,DACT3 |
| protein complex scaffold | MAGI1B,DLG1,CHCHD3,KLHL17,HOMER1,AKAP13,MPP7,DISC1,GNB2L1,SMARCD1 |
| protein binding | MID2,RSPH9,PPFIA2,GTF2H3,VARS2,PDZD3,CLOCKA,SNX8,MAPK12,GMNN |
| adenylate cyclase binding | ADRB2,CALM3,CALM2,AKAP5,AKAP12,CHRNA7,CALM1,ADCYAP1R1 |
| protein kinase A regulatory subunit binding | AKAP7,AKAP5,AKAP1,ARFGEF2,AKAP9,RYR2,ARFGEF1,ACBD3,KCNQ1,C2orf88 |
Interacting Protein
AKAP6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AKAP6 here. Most of them are supplied by our site. Hope this information will be useful for your research of AKAP6.
Resources
Related Services
Related Products
References
