AKAP3
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Official Full Name
A kinase (PRKA) anchor protein 3 -
Overview
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family, and is expressed in testis only. The encoded protein contains an RII-binding domain, and is predicted to participate in protein-protein interactions with the R-subunit of the PKA. This protein is localized to the ribs of the fibrous sheath in the principal piece of the sperm tail. It may function as a regulator of both motility- and head-associated functions such as capacitation and the acrosome reaction. -
Synonyms
AKAP3;A kinase (PRKA) anchor protein 3;A-kinase anchor protein 3;AKAP110;cancer/testis antigen 82;CT82;Fibrous Sheath Protein of 95 kDa;FSP95;SOB1;AKAP-3;AKAP 110;fibrousheathin 1;fibrousheathin I;fibrousheathin-1;fibrous sheath protein, 95k
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| AKAP3-1477M | Recombinant Mouse AKAP3 Protein | Mammalian Cell | Mouse | His |
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| Akap3-3026M | Recombinant Mouse Akap3, His-tagged | E.Coli or Yeast | Mouse | His | 864 |
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| AKAP3-3027B | Recombinant Bovine AKAP3, His-tagged | E.Coli or Yeast | Bovine | His | 858 |
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| AKAP3-108H | Recombinant Human AKAP3 Protein, His-tagged | E.coli | Human | His | Met1-Ser176 |
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| AKAP3-429M | Recombinant Mouse AKAP3 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| AKAP3-429M-B | Recombinant Mouse AKAP3 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
AKAP3 involved in several pathways and played different roles in them. We selected most pathways AKAP3 participated on our site, such as G Protein Signaling Pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with AKAP3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| G Protein Signaling Pathways | AKAP1B,GNGT2A,KCNJ3,AKAP12B,GNB3B,GNB5B,AKAP6,ARHGEF1A,AKAP10,AKAP4 |
Protein Function
AKAP3 has several biochemical functions, for example, protein binding,protein kinase A binding. Some of the functions are cooperated with other proteins, some of the functions could acted by AKAP3 itself. We selected most functions AKAP3 had, and list some proteins which have the same functions with AKAP3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | ENDOG,GATA1A,DTX3L,MYL12A,DNM1,FGF1,TMEM218,TIMM10,DBNDD2,UBA52 |
| protein kinase A binding | RARA,LRRK2,AKAP7,RPS3,AKAP5,AKAP6,AKAP14,AKAP4,DACT1,DACT2 |
Interacting Protein
AKAP3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AKAP3 here. Most of them are supplied by our site. Hope this information will be useful for your research of AKAP3.
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References
- Hanafusa, T; Mohamed, AEA; et al. Serological identification of Tektin5 as a cancer/testis antigen and its immunogenicity. BMC CANCER 12:-(2012).
- Song, MH; Choi, KU; et al. Identification of the cancer/testis antigens AKAP3 and CTp11 by SEREX in hepatocellular carcinoma. ONCOLOGY REPORTS 28:1792-1798(2012).
