ADCY7
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Official Full Name
adenylate cyclase 7 -
Overview
This gene encodes a membrane-bound adenylate cyclase that catalyses the formation of cyclic AMP from ATP and is inhibitable by calcium. The product of this gene is a member of the adenylyl cyclase class-4/guanylyl cyclase enzyme family that is characterized by the presence of twelve membrane-spanning domains in its sequences. -
Synonyms
ADCY7;adenylate cyclase 7;adenylate cyclase type 7;AC7;KIAA0037;adenylyl cyclase 7;ATP pyrophosphate-lyase 7;adenylate cyclase type VII;FLJ36387
Recombinant Proteins
- Mouse
- Human
- Zebrafish
- E.Coli or Yeast
- Wheat Germ
- Mammalian Cell
- E.coli
- HEK293
- His
- GST
- His&T7
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Adcy7-3179M | Recombinant Mouse Adcy7, His-tagged | E.Coli or Yeast | Mouse | His | 1099 |
|
| ADCY7-3180H | Recombinant Human ADCY7, His-tagged | E.Coli or Yeast | Human | His | 1080 |
|
| ADCY7-331H | Recombinant Human ADCY7 Protein, GST-tagged | Wheat Germ | Human | GST |
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| ADCY7-476H | Recombinant Human ADCY7 | Mammalian Cell | Human | His |
|
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| ADCY7-6932H | Recombinant Human ADCY7 protein, His & T7-tagged | E.coli | Human | His&T7 | Phe806~Gly1052 |
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| Adcy7-6933M | Recombinant Mouse Adcy7 protein, His & T7-tagged | E.coli | Mouse | His&T7 | Leu309~Glu491 |
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| ADCY7-7608Z | Recombinant Zebrafish ADCY7 | Mammalian Cell | Zebrafish | His |
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| ADCY7-0481H | Recombinant Human ADCY7 Protein (Phe806-Gly1052), N-His-tagged | E.coli | Human | His | Phe806-Gly1052 |
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| ADCY7-2430H | Recombinant Human ADCY7 Protein, His (Fc)-Avi-tagged | HEK293 | Human | His&Fc&Avi |
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| ADCY7-2430H-B | Recombinant Human ADCY7 Protein Pre-coupled Magnetic Beads | HEK293 | Human |
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Involved Pathway
ADCY7 involved in several pathways and played different roles in them. We selected most pathways ADCY7 participated on our site, such as Activation of GABAB receptors,Adenylate cyclase activating pathway,Adenylate cyclase inhibitory pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with ADCY7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Ca-dependent events | ADCY9,ADRBK1,PRKAR1AA |
| Adenylate cyclase activating pathway | ADCY3,ADCY6,ADCY8,ADCY9,ADCY1 |
| Aldosterone synthesis and secretion | CAMK2B,ADCY3,ITPR1,CALM4,PLCB4,DAGLB,CALML5,SLC14A2,AGTR1A,PRKCA |
| Bile secretion | SLCO1A6,SLC9A3,Car2,NR1H4,ADCY6,AQP4,ADCY3,ATP1B4,HMGCR,NCEH1 |
| Adrenergic signaling in cardiomyocytes | ATP2A2,PPP1CBL,PPP2R1A,GNAI2A,ATF6B,TPM2,TNNC1B,AGTR1,CALML5,AKT2L |
| Adenylate cyclase inhibitory pathway | ADCY1,ADCY8,ADCY9,ADCY6,ADCY3 |
| Activation of GABAB receptors | KCNJ3,KCNJ4,ADCY6,ADCY1,ADCY8,GNGT2A,KCNJ2,KCNJ5,ADCY9,KCNJ2A |
| Aquaporin-mediated transport | AQP6,AQP10B,PRKAR1AA,MIPB,AQP11,GNB5,ADCY6,AQP3A,ADCY3,ADCY8 |
Protein Function
ADCY7 has several biochemical functions, for example, ATP binding,adenylate cyclase activity,metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ADCY7 itself. We selected most functions ADCY7 had, and list some proteins which have the same functions with ADCY7. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP binding | UBE2A,DNAJA3A,KIF26A,MAPK14A,NME2B.2,RARS,CDKL4,TTLL11,HIPK3A,MAPK6 |
| adenylate cyclase activity | ADCY1,ADCY1B,ADCY8,GNAS,Adcy4,ADCY3,ADCY2B,ADCY9,ADCY6,ADCY1A |
| metal ion binding | GGTA1,ZNF718,ZNF620,CREB5,ZNF311,DGKD,ZNF23,BCL11B,HMOX1,ZFP524 |
Interacting Protein
ADCY7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ADCY7 here. Most of them are supplied by our site. Hope this information will be useful for your research of ADCY7.
PLSCR1;XRCC6;BUD31
ADCY7 Related Signal Pathway
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References
- Patocka, N; Sharma, N; et al. Serotonin Signaling in Schistosoma mansoni: A Serotonin-Activated G Protein-Coupled Receptor Controls Parasite Movement. PLOS PATHOGENS 10:-(2014).
- Knospe, M; Muller, CE; et al. The rat adenine receptor: pharmacological characterization and mutagenesis studies to investigate its putative ligand binding site. PURINERGIC SIGNALLING 9:367-381(2013).
