ADAMTSL4

  • Official Full Name

    ADAMTS-like 4
  • Overview

    This gene is a member of ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs)-like gene family and encodes a protein with protein with seven thrombospondin type 1 repeats. The thrombospondin type 1 repeat domain is found in many proteins with diverse biological functions including cellular adhesion, angiogenesis, and patterning of the developing nervous system. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
  • Synonyms

    ADAMTSL4;ADAMTS-like 4;thrombospondin repeat containing 1 , TSRC1;ADAMTS-like protein 4;DKFZP434K1772;ADAMTS like 4;ADAMTS like protein 4;ADAMTSL 4;MGC116260;MGC28749;OTTHUMP00000032789;OTTHUMP00000032790;Thrombospondin repeat containing 1;thrombospondin repeat protein 1;TSRC1;ADAMTSL-4;thrombospondin repeat-containing protein 1

Recombinant Proteins

  • Mouse
  • Human
  • Rat
  • Mammalian Cell
  • Wheat Germ
  • HEK293
  • His
  • GST
  • Non
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
ADAMTSL4-1327M Recombinant Mouse ADAMTSL4 Protein Mammalian Cell Mouse His
ADAMTSL4-32H Recombinant Human ADAMTSL4 protein, GST-tagged Wheat Germ Human GST 1-424 a.a.
ADAMTSL4-33H Recombinant Human ADAMTSL4 protein, GST-tagged Wheat Germ Human GST 1-424 a.a.
ADAMTSL4-508R Recombinant Rat ADAMTSL4 Protein Mammalian Cell Rat His
ADAMTSL4-27HCL Recombinant Human ADAMTSL4 cell lysate Human Non
ADAMTSL4-164R Recombinant Rat ADAMTSL4 Protein, His (Fc)-Avi-tagged HEK293 Rat His&Fc&Avi
ADAMTSL4-164R-B Recombinant Rat ADAMTSL4 Protein Pre-coupled Magnetic Beads HEK293 Rat
ADAMTSL4-328M Recombinant Mouse ADAMTSL4 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
ADAMTSL4-328M-B Recombinant Mouse ADAMTSL4 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    ADAMTSL4 involved in several pathways and played different roles in them. We selected most pathways ADAMTSL4 participated on our site, such as Metabolism of proteins,O-glycosylation of TSR domain-containing proteins,O-linked glycosylation, which may be useful for your reference. Also, other proteins which involved in the same pathway with ADAMTSL4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Metabolism of proteins DHPS,IGFBP2,HYOU1,TOMM22,MTX1,ADAMTSL5,ARSD,SPON2,SERP1,ADAMTS20
    O-glycosylation of TSR domain-containing proteins ADAMTS3,ADAMTS13,THSD1,SPON1,SPON1A,B3GALTL,SPON2,ADAMTS20,ADAMTS1,ADAMTSL3
    Post-translational protein modification TRAPPC9,ADAMTS8,PREB,NAPAA,SAE1,ALG14,RNF2,ZNF408,OTOP2,TRAPPC10
    O-linked glycosylation MUC13,MUC15,ADAMTS8,B3GALTL,ADAMTSL1,ADAMTS4,ADAMTS15,GALNTL5,A4GNT,SPON2

    Protein Function

    ADAMTSL4 has several biochemical functions, for example, metalloendopeptidase activity,protease binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ADAMTSL4 itself. We selected most functions ADAMTSL4 had, and list some proteins which have the same functions with ADAMTSL4. You can find most of the proteins on our site.

    Function Related Protein
    protease binding STIM1,TIMP4,Cstb,TP53,BDKRB2,TIMP2,SERPINA1D,RYR1,FURIN,TIMP1
    metalloendopeptidase activity UQCRC2,ADAMTS18,ECEL1,PMPCB,ADAMTS15A,GM12824,MIPEP,MMP13,MME,ADAM17A
    protein binding CDX1,LINC01588,DNMT3B,ERG,CDC7,PPP3CC,HMGB3,UBE2L3,ATF2,LOXL4

    Interacting Protein

    ADAMTSL4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ADAMTSL4 here. Most of them are supplied by our site. Hope this information will be useful for your research of ADAMTSL4.

    STK16;Hoxa1;CTSB;COL8A1;AQP1;TUBGCP4;SALL2;PLSCR1;SPRY2;SORBS3

    Resources

    References

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