ADAM19
-
Official Full Name
ADAM metallopeptidase domain 19 -
Overview
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This member is a type I transmembrane protein and serves as a marker for dendritic cell differentiation. It has been demonstrated to be an active metalloproteinase, which may be involved in normal physiological processes such as cell migration, cell adhesion, cell-cell and cell-matrix interactions, and signal transduction. It is proposed to play a role in pathological processes, such as cancer, inflammatory diseases, renal diseases, and Alzheimers disease. [provided by RefSeq, May 2013] -
Synonyms
ADAM19;ADAM metallopeptidase domain 19;MLTNB;FKSG34;MADDAM;disintegrin and metalloproteinase domain-containing protein 19;ADAM 19;meltrin-beta;metalloprotease-disintegrin meltrin beta;metalloprotease and disintegrin dendritic antigen marker;a disintegrin and metalloproteinase domain 19 (meltrin beta)
Recombinant Proteins
- Mouse
- Chicken
- Human
- Mus musculus
- Mammalian Cell
- HEK293
- E.coli
- E.coli expression system
- His
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| ADAM19-1281M | Recombinant Mouse ADAM19 Protein | Mammalian Cell | Mouse | His |
|
|
| ADAM19-4129C | Recombinant Chicken ADAM19 | Mammalian Cell | Chicken | His |
|
|
| ADAM19-9038HCL | Recombinant Human ADAM19 293 Cell Lysate | HEK293 | Human | Non |
|
|
| ADAM19-0046H | Recombinant Human ADAM19 Protein (Gly326-Ser699), N-His-tagged | E.coli | Human | His | Gly326-Ser699 |
|
| ADAM19-310M | Recombinant Mouse ADAM19 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
|
|
| ADAM19-310M-B | Recombinant Mouse ADAM19 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
|
||
| RFL-30771MF | Recombinant Full Length Mouse Disintegrin And Metalloproteinase Domain-Containing Protein 19(Adam19) Protein, His-Tagged | E.coli expression system | Mus musculus | His | Full L. Full Length of Mature Protein (205-920) |
|
Involved Pathway
ADAM19 involved in several pathways and played different roles in them. We selected most pathways ADAM19 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ADAM19 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
ADAM19 has several biochemical functions, for example, SH3 domain binding,metalloendopeptidase activity,zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ADAM19 itself. We selected most functions ADAM19 had, and list some proteins which have the same functions with ADAM19. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| zinc ion binding | TRIM35-28,TCF19,LMCD1,POLR2L,GATAD2A,Car8,ZCCHC7,RNF112,PYGO2,JADE3 |
| metalloendopeptidase activity | MMP8,ADAM25,ADAM1B,ADAMTS13,MMP1A,ADAM18,ADAMTS10,ADAM10B,UQCRC2,TLL1 |
| SH3 domain binding | INPP5J,GRB2,MYPN,ADAM15,SGIP1,ADAM12,ABI2,NCKIPSD,DOCK1,USP8 |
Interacting Protein
ADAM19 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ADAM19 here. Most of them are supplied by our site. Hope this information will be useful for your research of ADAM19.
ABI2;UBC;ESF1
Resources
Related Services
Related Products
References
- Dijkstra, A; Postma, DS; et al. Expression of ADAMs ("a disintegrin and metalloprotease") in the human lung. VIRCHOWS ARCHIV 454:441-449(2009).
- Bu, SM; Yang, YJ; et al. Developmental and-hormonal regulation of meltrin beta (ADAM19) expression in mouse testes during embryonic and postnatal life. LIFE SCIENCES 79:2112-2118(2006).
