ACYP2
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Official Full Name
acylphosphatase 2, muscle type -
Overview
Acylphosphatase can hydrolyze the phosphoenzyme intermediate of different membrane pumps, particularly the Ca2+/Mg2+-ATPase from sarcoplasmic reticulum of skeletal muscle. Two isoenzymes have been isolated, called muscle acylphosphatase and erythrocyte acylphosphatase on the basis of their tissue localization. This gene encodes the muscle-type isoform (MT). An increase of the MT isoform is associated with muscle differentiation. -
Synonyms
ACYP2;acylphosphatase 2, muscle type;acylphosphatase-2;muscle type isozyme;Acylphosphatase 2;Acylphosphatase 2 muscle type;Acylphosphatase;Acylphosphatase muscle type isozyme;Acylphosphatase2;Acylphosphate phosphohydrolase 2;Acylphosphate phosphohydrolase;ACYM;ACYP 2;ACYP;ACYP2_HUMAN;Muscle type acylphosphatase 2;OTTHUMP00000159620;OTTHUMP00000200601;OTTHUMP00000200602;acylphosphatase, muscle type isozyme
Recombinant Proteins
- Mouse
- Human
- Cynomolgus
- Guinea pig
- Rat
- Chicken
- Mammalian Cell
- E.coli
- Wheat Germ
- E.Coli or Yeast
- HEK293
- Mammalian cells
- HEK293T
- In Vitro Cell Free System
- His
- GST
- Non
- Flag
- Myc&DDK
- His&Fc&Avi
Involved Pathway
ACYP2 involved in several pathways and played different roles in them. We selected most pathways ACYP2 participated on our site, such as Pyruvate metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with ACYP2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Pyruvate metabolism | MDH2,LDHA,ackA,ALDH1B1,DLDH,LDHAL6B,PDHA1,ACOT12,PKMB,MPC1 |
Protein Function
ACYP2 has several biochemical functions, for example, acylphosphatase activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ACYP2 itself. We selected most functions ACYP2 had, and list some proteins which have the same functions with ACYP2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| acylphosphatase activity | ACYP1 |
| protein binding | RAB35,ZNF397,MRPL1,UBASH3A,NUP35,RPS6KA3,CX3CL1,FAM108A1,KLF17,IRF2BP1 |
Interacting Protein
ACYP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ACYP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ACYP2.
SULT2B1;CREBZF
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References
- Won, HH; Lee, J; et al. Polymorphic markers associated with severe oxaliplatin-induced, chronic peripheral neuropathy in colon cancer patients. CANCER 118:2828-2836(2012).
- Chong, SH; Lee, C; et al. Structural and Thermodynamic Investigations on the Aggregation and Folding of Acylphosphatase by Molecular Dynamics Simulations and Solvation Free Energy Analysis. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 133:7075-7083(2011).
