ACRBP
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Official Full Name
acrosin binding protein -
Overview
The protein encoded by this gene is similar to proacrosin binding protein sp32 precursor found in mouse, guinea pig, and pig. This protein is located in the sperm acrosome and is thought to function as a binding protein to proacrosin for packaging and condensation of the acrosin zymogen in the acrosomal matrix. This protein is a member of the cancer/testis family of antigens and it is found to be immunogenic. In normal tissues, this mRNA is expressed only in testis, whereas it is detected in a range of different tumor types such as bladder, breast, lung, liver, and colon. -
Synonyms
ACRBP;acrosin binding protein;acrosin-binding protein;cancer/testis antigen 23;CT23;OY TES 1;proacrosin binding protein sp32;SP32;cancer/testis antigen OY-TES-1;OY-TES-1;FLJ51160
Recombinant Proteins
- Mouse
- Human
- Rat
- Mammalian Cell
- E.coli
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- E. coli
- His
- HIS
- GST
- Non
- His&Fc&Avi
- N-His
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| ACRBP-1219M | Recombinant Mouse ACRBP Protein | Mammalian Cell | Mouse | His |
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| ACRBP-155H | Recombinant Human ACRBP Protein, HIS-tagged | E.coli | Human | HIS |
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| ACRBP-187H | Recombinant Human ACRBP Protein, GST-Tagged | Wheat Germ | Human | GST |
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| ACRBP-465R | Recombinant Rat ACRBP Protein | Mammalian Cell | Rat | His |
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| ACRBP-9080HCL | Recombinant Human ACRBP 293 Cell Lysate | HEK293 | Human | Non |
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| ACRBP-121R | Recombinant Rat ACRBP Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| ACRBP-121R-B | Recombinant Rat ACRBP Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| ACRBP-267M | Recombinant Mouse ACRBP Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| ACRBP-267M-B | Recombinant Mouse ACRBP Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| ACRBP-811HF | Recombinant Full Length Human ACRBP Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 543 amino acids |
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| IL1A-1018H | Recombinant Human IL1A protein, His-tagged | E. coli | Human | N-His | 1-271 aa |
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Involved Pathway
ACRBP involved in several pathways and played different roles in them. We selected most pathways ACRBP participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ACRBP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
ACRBP has several biochemical functions, for example, molecular_function. Some of the functions are cooperated with other proteins, some of the functions could acted by ACRBP itself. We selected most functions ACRBP had, and list some proteins which have the same functions with ACRBP. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| molecular_function | LPAR5,TMEM143,PIGO,TMCO3,TARS2,CRYBB1L3,HOXC12,ACNAT2,SPRR2A2,TMEM69 |
Interacting Protein
ACRBP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ACRBP here. Most of them are supplied by our site. Hope this information will be useful for your research of ACRBP.
Resources
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References
- Kongmanas, K; Kruevaisayawan, H; et al. Proteomic Characterization of Pig Sperm Anterior Head Plasma Membrane Reveals Roles of Acrosomal Proteins in ZP3 Binding. JOURNAL OF CELLULAR PHYSIOLOGY 230:449-463(2015).
- Hemminger, JA; Toland, AE; et al. Expression of cancer-testis antigens MAGEA1, MAGEA3, ACRBP, PRAME, SSX2, and CTAG2 in myxoid and round cell liposarcoma. MODERN PATHOLOGY 27:1238-1245(2014).
