ABT1
-
Official Full Name
activator of basal transcription 1 -
Overview
Basal transcription of genes by RNA polymerase II requires the interaction of TATA-binding protein (TBP) with the core region of class II promoters. Studies in mouse suggest that the protein encoded by this gene likely activates basal transcription from class II promoters by interaction with TBP and the class II promoter DNA. -
Synonyms
activator of basal transcription 1;Basal transcriptional activator;hABT1;TATA-binding protein-binding protein;ABT1
Recombinant Proteins
- Mouse
- Human
- Zebrafish
- Rat
- Mammalian Cell
- Wheat Germ
- HEK293T
- HEK293
- In Vitro Cell Free System
- His
- GST
- Non
- Myc&DDK
- His&Fc&Avi
Involved Pathway
ABT1 involved in several pathways and played different roles in them. We selected most pathways ABT1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ABT1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
ABT1 has several biochemical functions, for example, DNA binding,nucleotide binding,poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ABT1 itself. We selected most functions ABT1 had, and list some proteins which have the same functions with ABT1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| DNA binding | HMGA1,RMI2,NFIL3,TOP2A,HOXC3A,ZNF227,HIST2H3C,H2AFB1,SPHK1,KIF4 |
| poly(A) RNA binding | HSP90AA1,TSNAX,REXO4,SART1,DDX18,GDI2,EIF3G,ELAVL2,KIAA1429,LARP4 |
| nucleotide binding | ARL4AB,SYNCRIPL,MYHZ1.2,HNRNPA0L,EEF2B,RBM39,RBM12B1,TAF15,NAIP7,TGFBR1A |
| protein binding | TMEM43,CD58,ZNHIT3,STIM2,ESR1,CELSR1,NGF,SASS6,GLI2,FBXL19 |
| transcription coactivator activity | MED12,TFDP1A,CCNE1,CTNNB1,SMARCD1,SERTAD2,HCFC1,RNF4,JMY,IL31RA |
Interacting Protein
ABT1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ABT1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ABT1.
EMD;FAM9B;SYNE4;CEP70;CDCA7L;CCDC136;LZTS2
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