ABCF1
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Official Full Name
ATP-binding cassette, sub-family F (GCN20), member 1 -
Overview
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the GCN20 subfamily. Unlike other members of the superfamily, this protein lacks the transmembrane domains which are characteristic of most ABC transporters. This protein may be regulated by tumor necrosis factor-alpha and play a role in enhancement of protein synthesis and the inflammation process. -
Synonyms
ABCF1;ATP-binding cassette, sub-family F (GCN20), member 1;ABC50;ATP-binding cassette sub-family F member 1;EST123147;TNF-alpha-stimulated ABC protein;TNFalpha-inducible ATP-binding protein;ATP-binding cassette 50 (TNF-alpha stimulated);ABC27
Recombinant Proteins
- Human
- Zebrafish
- Rhesus macaque
- Rat
- Mouse
- Wheat Germ
- Mammalian Cell
- E.coli
- HEK293
- GST
- His
- His&T7
- Non
- His&Fc&Avi
Involved Pathway
ABCF1 involved in several pathways and played different roles in them. We selected most pathways ABCF1 participated on our site, such as ABC-family proteins mediated transport,Transmembrane transport of small molecules, which may be useful for your reference. Also, other proteins which involved in the same pathway with ABCF1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| ABC-family proteins mediated transport | ABCC2,KCNJ11,ABCB8,EIF2S1,ABCG4B,ABCA8,ABCA4A,EIF2S1A,EIF2S3,ABCE1 |
| Transmembrane transport of small molecules | SLC39A2,SLC30A8,SLC2A7,SLC43A2B,SLC35A2,ABCD3B,SLC13A4,RHCG,SLC24A6,SLC38A3 |
Protein Function
ABCF1 has several biochemical functions, for example, ATP binding,ATPase activity,poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ABCF1 itself. We selected most functions ABCF1 had, and list some proteins which have the same functions with ABCF1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| poly(A) RNA binding | SEC61B,MYH9,EEF1A1,HIST2H4A,SART3,ATP5A1,GTPBP4,PPIA,ZAK,DDX54 |
| ribosome binding | CPEB4,CPEB3,RICTOR,ERI1,SEC61A1,SEC61B,ETF1,EIF2S1,IGHMBP2,CPEB1 |
| ATP binding | ITPK1A,PRKCG,MCM8,HSPA12B,CHEK2,ACSL4,UBE2L3,SYN3,MAT2A,TOR1A |
| translation factor activity, RNA binding | EEF1D,CPEB1B,EEF1A2,GTF2H2,EIF5,GTF2H3,CPEB2,PPP1R2P9,EIF4G3,EIF4H |
| protein binding | TP63,RPL37A,DDX58,FAM126B,HDDC2,CCDC86,SPRY2,MRPL51,MPZL2B,PIP5K1C |
| ATPase activity | ABCF2,ERCC3,VCP,PSMC3,ABCG2B,ATAD1A,ACTC1,WRNIP1,ABCD1,DYNC1H1 |
| translation activator activity | PAIP1,PABPC1,RPS27L,DAZL,BOLL,LARP1 |
Interacting Protein
ABCF1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ABCF1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ABCF1.
SRPK1;PINX1;LYAR;PRKAB1;ITGB3BP;CNOT1;ere_dna;NOP56;EED;FN1;Fbl;HDGF;SNW1;EMC2;IFI16;TIGD6;CDC5L
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