AACS
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Official Full Name
acetoacetyl-CoA synthetase -
Overview
activates acetoacetate to its CoA ester. -
Synonyms
AACS;acetoacetyl-CoA synthetase;ACSF1;acyl CoA synthetase family member 1;FLJ12389;SUR 5;Acetoacetate CoA ligase;ACSF 1;FLJ41251;Homolog of C. elegans supressor of ras 5;Protein sur 5 homolog;SUR5;protein sur-5 homolog;acetoacetate-CoA ligase;acyl-CoA synthetase family member 1;homolog of C. elegans supressor of ras 5 (sur-5);SUR-5
Recombinant Proteins
- Human
- Mouse
- Zebrafish
- Chicken
- Cynomolgus
- Rat
- Insect Cells
- Wheat Germ
- Mammalian Cell
- Insect Cell
- E.coli
- HEK293
- In Vitro Cell Free System
- Mouse
- His
- GST
- Non
- His&Fc&Avi
Involved Pathway
AACS involved in several pathways and played different roles in them. We selected most pathways AACS participated on our site, such as Valine, leucine and isoleucine degradation,Butanoate metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with AACS were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Butanoate metabolism | ACADS,EHHADH,BDH2,ACSM1,GAD1,HMGCLL1,OXCT1A,ACAT2,ACSM2,HMGCS2 |
| Valine, leucine and isoleucine degradation | ACAA2,HADHB,OXCT2A,HMGCL,MCCC1,OXCT1,ALDH7A1,HSD17B10,BCAT2,ALDH9A1 |
Protein Function
AACS has several biochemical functions, for example, ATP binding,acetoacetate-CoA ligase activity,butyrate-CoA ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by AACS itself. We selected most functions AACS had, and list some proteins which have the same functions with AACS. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| butyrate-CoA ligase activity | ACSM2,ACSM2B,ACSM3,ACSM1,Acsm2a,ACSM5,ACSM4,PPP1CA |
| protein binding | KCTD5,MINK1,SNCA,FAM127B,SMN1,CALB1,NPLOC4,GNAS,BATF3,HMGB2 |
| ATP binding | ORC5,SLC22A5,RIOK2,PFKFB2A,EP400,ATP1A1A.5,NUBP2,CLK1,MCM5,P2RX3B |
Interacting Protein
AACS has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AACS here. Most of them are supplied by our site. Hope this information will be useful for your research of AACS.
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