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SALL1

Official Full Name

spalt-like transcription factor 1
Overview

The protein encoded by this gene is a zinc finger transcriptional repressor and may be part of the NuRD histone deacetylase complex (HDAC). Defects in this gene are a cause of Townes-Brocks syndrome (TBS) as well as bronchio-oto-renal syndrome (BOR). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Synonyms

SALL1; spalt-like transcription factor 1; TBS; HSAL1; Sal-1; ZNF794; HEL-S-89; sal-like protein 1; zinc finger protein 794; zinc finger protein SALL1; zinc finger protein Spalt-1; epididymis secretory protein Li 89;

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	SALL1-2075HCL	Recombinant Human SALL1 293 Cell Lysate	HEK293	Non		Inquiry
Chicken	SALL1-6272C	Recombinant Chicken SALL1	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
Other Resource

SALL1 involved in several pathways and played different roles in them. We selected most pathways SALL1 participated on our site, such as Wnt Signaling Pathway NetPath, which may be useful for your reference. Also, other proteins which involved in the same pathway with SALL1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Wnt Signaling Pathway NetPath	ROR2;ANKRD6;HIPK2;MTAP1B;PAX2;BRD7;CSNK2A1P;NR5A1;SALL1

SALL1 has several biochemical functions, for example, DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding, beta-catenin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SALL1 itself. We selected most functions SALL1 had, and list some proteins which have the same functions with SALL1. You can find most of the proteins on our site.

Function	Related Protein
DNA binding	PBX1A;HLTF;MIXL1;SMAD3A;ING2;HIST1H2B8;NPAS4A;TFDP1A;ZFP775
RNA polymerase II core promoter proximal region sequence-specific DNA binding	ZKSCAN3;NEUROD6;DPF2;PBX1;TFAP2E;MEOX1;FOSL1A;CREB3L2;TCF7L2
beta-catenin binding	AXIN2;CALCOCO1;TBL1XR1;CARM1;SLC9A3R1;PROP1;APC;PTPRU;Ar
chromatin binding	SMAD2;HDAC2;SP140;LDB1;PCGF2;ZGLP1;CDC45;POLR2B;NFKB1
contributes_to histone deacetylase activity	SIN3B;BRMS1L;BRMS1LA;SUDS3;BRMS1;SALL1;SIN3AA;SIN3A
metal ion binding	TNKS2;CNOT6L;CNDP1;PHLPP2;ZFP367;HRG;TPP1;B3GAT3;TNNI3
protein binding	URM1;ZNF224;CD19;PDE9A;TOP1;MRPL40;WDR74;TWIST1;CXCL2
sequence-specific DNA binding	SOX30;FOXP1B;FOXO1B;FOXD2;ZNF831;HOXA13B;NR6A1A;NR1D2B;NKX2
transcription factor activity, sequence-specific DNA binding	ZNF484;HNF1BB;HEYL;EGR2B;RXRAA;MYCLB;DDIT3;FOS;ATOH1
transcription regulatory region DNA binding	SOX17;SMAD7;SALL2;ZFP335;ARRB1;ARID5B;MEN1;SALL3B;AIRE
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding	JDP2;NFATC4;SPI1;ZNF217;MXD1;TCF3;NKX6-1;GFI1;ZBTB20

SALL1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SALL1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SALL1.