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MAML2

Official Full Name

mastermind-like 2 (Drosophila)
Overview

Acts as a transcriptional coactivator for NOTCH proteins. Has been shown to amplify NOTCH-induced transcription of HES1. Potentiates activation by NOTCH3 and NOTCH4 more efficiently than MAML1 or MAML3.
Synonyms

MAML2; mastermind-like 2 (Drosophila); MAM2; MAM3; MAM-3; MLL-MAML2; mastermind-like protein 2; mam-2;

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	MAML2-718H	Recombinant Human MAML2, GST-tagged	E.coli	GST	805-1153aa	$319 / 25μg

Involved Pathway
Protein Function
Interacting Protein
MAML2 Related Signal Pathway

MAML2 involved in several pathways and played different roles in them. We selected most pathways MAML2 participated on our site, such as Notch signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with MAML2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Notch signaling pathway	PSEN1;DVL3A;HER15.1;MIB1;JAG1A;LNX1;NOTCH2;SNW1;MFAP2

MAML2 has several biochemical functions, for example, transcription coactivator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MAML2 itself. We selected most functions MAML2 had, and list some proteins which have the same functions with MAML2. You can find most of the proteins on our site.

Function	Related Protein
transcription coactivator activity	TFAP2B;SUB1;MTF1;WWTR1;MAML1;DYRK1B;TAF1;MKL1;MAGED1

MAML2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MAML2 here. Most of them are supplied by our site. Hope this information will be useful for your research of MAML2.

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