Creative Biomart Blog

Thu, 2016/07/14

Neural Epigenetic Regulation: Chromatin Remodeling Regulates Genes and Neural Coding

This article is published by Yue Yang in Science Magazine (Science 15 Jul 2016: Vol. 353, Issue 6296, pp. 300-305 DOI: 10.1126/science.aad4225). The authors share their findings about nucleosome remodeling and deacetylase complex (NuRD) and Chd4 in Neural Epigenetic Regulation through Chromatin Remodeling. Creative Biomart can provide some production for related research application. [table caption="Related Products" width="800" colwidth="100|280|180" colalign="left|left|center|center|center"] Cat. #,Product name,Source(Host),Species,Conjugate CHD4-2793H,Recombinant Human CHD4 protein GST-tagg

Fri, 2016/07/01

Autoimmune Diseases Therapy: Targeted by Chimeric Antigen Receptor T cells

This article is reproduced from Science Magazine (Science 01 Jul 2016: Vol. 353, Issue 6294, pp. 14 DOI: 10.1126/science.353.6294.14) Fighting autoimmunity with immune cells. In this article, the possibility of the solving some autoimmune diseases with immune cells is discussed. Autoimmune diseases share a grim similarity with cancer: People's own cells become their enemies. But a new study published online in Science reveals a happier parallel, suggesting that a therapy designed to harness the immune system to attack cancer cells may also cull the turncoat immune cells behind certain autoim

Thu, 2016/06/23

Error-correcting Reverse Transcriptase: Increase the Precision of Transcriptomics Methods with Proofreading Function

Ellefson et al. construct a reverse transcriptase using in vitro directed evolution and protein engineering from a prokaryotic DNA polymerase. This reverse transcriptase shows increased fidelity as compared to natural reverse transcriptases and increases the precision of transcriptomics methods. Ellefson et al. published their results in Science Magazine (Science 24 Jun 2016: Vol. 352, Issue 6293, pp. 1590-1593 DOI: 10.1126/science.aaf5409). The article is followed: The molecular basis for life rests on the information flow between DNA, RNA, and proteins. Early notions of a unidirectional ce

Tue, 2016/06/21

Therapeutic Targets for Skin Cancer: MET Signaling and RAS Converge on EGFR

New findings from Science Signaling (21 Jun 2016: Vol. 9, Issue 433, pp. ra62 DOI: 10.1126/scisignal.aaf5106), this article indicates that EGFR pathway may offer potential therapeutic targets for patients. Here we provide part of this wonderful article. Read full details: http://stke.sciencemag.org/content/9/433/ra62. [table caption="Related Products" width="800" colwidth="100|250|180" colalign="left|center|center|center|center"] No.,Gene name,Product type,Product number 1,EGFR,Recombinant Protein,48 2,MET,Recombinant Protein,42 3,HGF,Recombinant Protein,30 4,HRAS,Recombinant Protein,19 [/tab

Fri, 2016/06/17

New Fluorescent Method to Detect Nicotinamide Adenine Dinucleotide (NAD+)

Researchers have found a new method to detect NAD+, and they published their wonderful work on Science Magazine: http://science.sciencemag.org/content/352/6292/1474. Creative Biomart provides NAD+ related protein products for research applications. [table caption="Related Products" width="800" colwidth="100|200|180" colalign="left|left|center|center|center"] Cat. #,Product name,Source(Host),Species,Conjugate PARP1-4276R,Recombinant Rat PARP1 Protein,Mammalian Cells,Rat,His PARP2-12373M,Recombinant Mouse PARP2 Protein,Mammalian Cells,Mouse,His PARP4-156H,Recombinant Human PARP4 protein GST-ta

Thu, 2016/06/16

Perspective: Using microRNAs to Induce Single-cell variability

Newest article from Science Magazine: http://science.sciencemag.org/content/352/6292/1390 A single zygote with a defined DNA sequence gives rise to all the varied cells of the mammalian body. This variety of cell fates may arise in part from cell-to-cell variability in the gene expression programs of embryonic stem cells (ESCs). Three recent studies have taken different approaches to characterizing this variability in gene expression in stem cells. These results suggest that microRNAs (miRNAs) could play an important role in controlling and generating this variability. Pluripotent stem cells

Thu, 2016/05/26

Insight: the Mechanism to Maintain the Spindle at the Cell Center during Mitosis

Cell division is the most important and common events in life. However, the entire mechanism of cell division is still mysterious for us. Recently, scientists (Carlos Garzon-Coral, Horatiu A. Fantana, Jonathon Howard) found A force-generating machinery that can maintain the spindle at the cell center during mitosis, and they published their findings on Science Magazine (Science 27 May 2016: Vol. 352, Issue 6289, pp. 1124-1127 DOI: 10.1126/science.aad9745). Here, let us to appreciate their wonderful article. (Don’t forget that Creative Biomart can provide you molecular tools in cell division r

Thu, 2016/05/19

Global Standards for Stem-cell Research

Stem-cell research is one of the most popular research areas. More and more scientists pay their attention to this field. Now, new guidelines from the International Society for Stem Cell Research offer a model for self-regulation in contentious areas, write Jonathan Kimmelman and colleagues. What’s more, Creative Biomart provides you the best protein products for stem-cell research. Stem-cell research offers tremendous promise for biomedicine. It also raises vexing ethical and policy challenges. It can involve the destruction, creation and modification of human embryos, and has led to the pre