Cat.No.: | PE-1819 |
Product Name: | JMJD2C tudor domain (human recombinant) |
Description: | Tudor domains are small protein structural motifs of ~50 amino acids related to the “royal family” of methyl readers, which also includes chromo, MBT, PWWP, and Agenet-like domains. Tudor domains occur either alone, in tandem, or with other domains and are found in many proteins that are involved in RNA metabolism, germ cell development, transposon silencing, DNA damage response, histone modification, and chromatin remodeling. The tudor domains recognize symmetric methylated arginine or methylated lysine residues. JMJD2C is an α-ketoglutarate-dependent Fe (II) oxygenase that catalyzes the demethylation of trimethylated histone H3 at lysine residues 9 and 36 (H3K9me3 and H3K36me3). This protein product contains the tandem tudor domains of JMJD2C. |
Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
Molecular Weight: | 39.89 kDa |
Species: | human |
Formulation: | 50 mM Tris, pH 7.5, containing 150 mM sodium chloride and 20% glycerol |
Accession#: | Q9H3R0 |
Alternative Names: | GASC-1 Protein;KDM4C;Lysine-specific Demethylase 4C;JmjC Domain-containing Histone Demethylation Protein 3C;Jumonji Domain-containing Protein 2C |
Tag: | GST |
Expression System: | E. coli |
Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Product Types | ||
◆ Bioactive Small Molecules | ||
BSM-0027 | UNC0321 (trifluoroacetate salt) | Inquiry |
◆ Antibodies | ||
EAb-0072 | JMJD6 Polyclonal Antibody | Inquiry |
EAb-0074 | JMJD2c Polyclonal Antibody | Inquiry |
EAb-0075 | JMJD2b Polyclonal Antibody | Inquiry |
EAb-0076 | JMJD2A Polyclonal Antibody | Inquiry |
Related Gene / Proteins | |||
JMJD | JMJD1A | JMJD1B | JMJD1C |
JMJD2 | JMJD2A | JMJD2B | JMJD2C |
JMJD2D | JMJD2E | JMJD2F | JMJD3 |
JMJD4 | JMJD5 | JMJD6 |
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