PRMT3 (human recombinant)


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Cat.No.:  PE-1811
Product Name:  PRMT3 (human recombinant)
Description:  Protein arginine methyltransferases (PRMTs) are a family of enzymes with highly conserved catalytic domains that catalyze the transfer of a methyl group from S-adenosyl-L-methionine (SAM) to a specific arginine residue in a target protein. PRMT3 is a type-1 PRMT, catalyzing the formation of ω-NG-monomethylarginine (MMA) and asymmetric ω-NG,NG-dimethylarginine (ADMA). In contrast to other members of the PRMT family, PRMT3 is predominantly cytoplasmic and constitutively expressed. PRMT3 contains a C2H2-type zinc finger which is responsible for substrate recognition/binding. PRMT3 has been shown to interact with the 40S ribosomal protein S2 (rpS2) and methylate arginine residues in the arginine-glycine (RG) repeat region in the amino-terminus of rpS2.
Storage:  Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles.
Molecular Weight:  86.6 kDa
Purity:  ≥90%
Species:  human
Formulation:  50 mM Tris-HCl, pH 8.0, containing 150 mM sodium chloride and 20% glycerol
Accession#:  O60678
Alternative Names:  Heterogeneous Nuclear Ribonucleoprotein Methyltransferase-like Protein 3;Protein Arginine N-methyltransferase 3
Tag:  GST
Expression System:  E. coli
Warning:  This product is for research use only. Not for use in diagnostic or therapeutic procedures.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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