| Cat.No.: | PE-1487 |
| Product Name: | Recombinant Human MORF4L2, His-tagged |
| Product Overview: | Recombinant human MORF4L2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. |
| Description: | MORF4L2 is a member of the mortality factor (MORF) family of transcriptional regulator that is involved in cell growth, regulation and senescence. This protein localizes to the nucleus, and it has a protein kinase C phosphorylation site as well as a tyrosine phosphorylation site. It interacts with the Rb tumor suppressor through its helix-loop-helix and leucine zipper regions. It also has histone deacetylase activity and can either repress or promote the activity of the B-Myb promoter depending on the tissue. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Molecular Weight: | 34.4 kDa (308aa) confirmed by MALDI-TOF(Molecular weight on SDS-PAGE will appear higher) |
| Purity: | > 90% by SDS - PAGE |
| Species: | Human |
| Formulation: | Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol; 1mM DTT |
| Tag: | His |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MSSRKQGSQP RGQQSAEEEN FKKPTRSNMQ RSKMRGASSG KKTAGPQQKN LEPALPGRWG GRSAENPPSG SVRKTRKNKQ KTPGNGDGGS TSEAPQPPRK KRARADPTVE SEEAFKNRME VKVKIPEELK PWLVEDWDLV TRQKQLFQLP AKKNVDAILE EYANCKKSQG NVDNKEYAVN EVVAGIKEYF NVMLGTQLLY KFERPQYAEI LLAHPDAPMS QVYGAPHLLR LFVRIGAMLA YTPLDEKSLA LLLGYLHDFL KYLAKNSASL FTASDYKVAS AEYHRKAL |
| Expression System: | E. coli |
| Concentrations: | 0.5 mg/ml (determined by Bradford assay) |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene Name: | MORF4L2 mortality factor 4 like 2 [ Homo sapiens ] |
| Gene ID NCBI: | 9643 |
| Synonyms: | MORF4L2; MRGX; MORFL2; KIAA0026; mortality factor 4-like protein 2; MSL3-2 protein; protein MSL3-2; OTTHUMP00000023750; OTTHUMP00000023751; OTTHUMP00000023752; OTTHUMP00000023753; OTTHUMP00000023754; OTTHUMP00000023756; MORF-related gene X protein; transcription factor-like protein MRGX |
| mRNA Refseq: | NM_001142418 |
| Protein Refseq: | NP_001135890 |
| MIM: | 300409 |
| UniProt ID: | Q15014 |
| Chromosome Location: | Xq22 |
| Function: | protein binding |
| Product Types | ||
| ◆ Bioactive Small Molecules | ||
| BSM-0174 | MOZ-IN-3 | Inquiry |
| ◆ Synthetic Peptides | ||
| SP-0174 | Human KAT8 / MYST1 / MOF peptide | Inquiry |
| ◆ Extracts & Lysates | ||
| EL-0221 | Recombinant Human MORF4L2 293 Cell Lysate | Inquiry |
| ◆ Antibodies | ||
| EAb-0695 | MORC2 Polyclonal Antibody | Inquiry |
| EAb-0779 | MORC2 Polyclonal Antibody, HRP Conjugated | Inquiry |
| Related Gene / Proteins | |||
| MOF | MORC2 | MORC3 | MORF |
| MORF4L2 | MOZ | ||
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