| Cat.No.: | PE-1445 |
| Product Name: | Recombinant Human CHD2 |
| Product Overview: | Recombinant full length Human CHD2 with an N terminal proprietary tag; Predicted MWt 81.22 kDa. |
| Description: | The CHD family of proteins is characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. CHD genes alter gene expression possibly by modification of chromatin structure thus altering access of the transcriptional apparatus to its chromosomal DNA template. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Appearance: | Liquid |
| Molecular Weight: | 81.220kDa inclusive of tags |
| Species: | Human |
| Amino Acid Sequence: | MMRNKDKSQEEDSSLHSNASSHSASEEASGSDSGSQSESE QGSDPGSGHGSESNSSSESSESQSESESESAGSKSQPVLP EAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPS RFNIKEEASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQ EQGTSAESEPEQKKVKARRPVPRRTVPKPRVKKQPKTQRG KRKKQDSSDEDDDDDEAPKRQTRRRAAKNVSYKEDDDFET DSDDLIEMTGEGVDEQQDNSETIEKVLDSRLGKKGATGAS TTVYAIEANGDPSGDFDTEKDEGEIQYLIKWKGWSYIHST WESEESLQQQKVKGLKKLENFKKKEDEIKQWLGKVSPEDV EYFNCQQELASELNKQYQIVERVIAVKTSKSTLGQTDFPA HSRKPAPSNEPEYLCKWMGLPYSECSWEDEALIGKKFQNC IDSFHSRNNSKTIPTRECKALKQRPRFVALKKQPAYLGGE NLELRDYQLEGLNWLAHSWCK |
| Sequence Similarities: | Belongs to the SNF2/RAD54 helicase family.Contains 2 chromo domains.Contains 1 helicase ATP-binding domain.Contains 1 helicase C-terminal domain. |
| Expression System: | Wheat germ |
| Protein Length: | 501 amino acids |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene Name: | CHD2 chromodomain helicase DNA binding protein 2 [ Homo sapiens ] |
| Gene ID NCBI: | 1106 |
| Official Symbol: | CHD2 |
| Synonyms: | CHD2; chromodomain helicase DNA binding protein 2; chromodomain-helicase-DNA-binding protein 2; DKFZp547I1315; DKFZp686E01200; DKFZp781D1727; FLJ38614; |
| mRNA Refseq: | NM_001042572 |
| Protein Refseq: | NP_001036037 |
| MIM: | 602119 |
| UniProt ID: | O14647 |
| Chromosome Location: | 15q26 |
| Function: | ATP binding; ATP-dependent DNA helicase activity; DNA binding; helicase activity; hydrolase activity; |
| Product Types | ||
| ◆ Extracts & Lysates | ||
| EL-0147 | Recombinant Human CHAF1A 293 Cell Lysate | Inquiry |
| EL-0167 | Recombinant Human CHAF1B 293 Cell Lysate | Inquiry |
| EL-0211 | Recombinant Human CHD2 Cell Lysate | Inquiry |
| ◆ Synthetic Peptides | ||
| SP-0180 | Mouse Chd7 peptide | Inquiry |
| ◆ Antibodies | ||
| EAb-0199 | CHRDL1 Monoclonal Antibody (3H1-F6-A10) | Inquiry |
| Related Gene / Proteins | |||
| CHAF1A | CHAF1B | CHD1 | CHD2 |
| CHD3 | CHD4 | CHD5 | Chd7 |
| CHD8 | CHD9 | CHEK2 | CHRAC1 |
| CHRDL1 | |||
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