| Cat.No.: | PE-1332 |
| Product Name: | Recombinant Human KAT8 , GST-tagged |
| Product Overview: | Recombinant human KAT8 (2-467; contains the catalytic domain) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. |
| Description: | KAT8 (MYST1) or MYST histone acetyltransferase 1 is a signaling protein that belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein which play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. MYST1 have a chromodomain that involved in protein-protein interactions and targeting transcriptional regulators to chromatin.MYST histone acetyltransferase 1 is also involved in ATM function. |
| Applications: | Western Blot |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Molecular Weight: | ~83 kDa |
| Purity: | >80% |
| Species: | Human |
| Formulation: | Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
| Tag: | GST |
| Expression System: | Sf9 Insect Cells |
| Protein Length: | 2-467 aa |
| Concentrations: | 0.1 μg/μ |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene Name: | KAT8 K(lysine) acetyltransferase 8 [ Homo sapiens ] |
| Gene ID NCBI: | 84148 |
| Synonyms: | KAT8; K(lysine) acetyltransferase 8; MYST histone acetyltransferase 1 , MYST1; histone acetyltransferase KAT8; FLJ14040; hMOF; MOF; MYST-1; lysine acetyltransferase 8; histone acetyltransferase MYST1; MYST histone acetyltransferase 1; MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1; probable histone acetyltransferase MYST1; ortholog of Drosophila males absent on the first (MOF); MYST1; |
| mRNA Refseq: | NM_032188 |
| Protein Refseq: | NP_115564 |
| MIM: | 609912 |
| UniProt ID: | Q9H7Z6 |
| Chromosome Location: | 16p11.1 |
| Function: | acetyltransferase activity; histone acetyltransferase activity; contributes_to histone acetyltransferase activity (H4-K16 specific); contributes_to histone acetyltransferase activity (H4-K5 specific); contributes_to histone acetyltransferase activity (H4-K8 specific); metal ion binding; methylated histone residue binding; protein binding; transcription factor binding; |
| Product Types | ||
| ◆ Bioactive Small Molecules | ||
| BSM-0073 | Anacardic Acid | Inquiry |
| ◆ Antibodies | ||
| EAb-0073 | KAT8 Polyclonal Antibody | Inquiry |
| ◆ Cell Lines | ||
| CL-0083 | Human KAT2A Knockout Cell Line 1bp insertion | Inquiry |
| CL-0085 | Human KAT2B Knockout Cell Line 31bp deletion | Inquiry |
| ◆ Extracts & Lysates | ||
| EL-0159 | Recombinant Human MYST2 293 Cell Lysate | Inquiry |
| Related Gene / Proteins | |||
| Kaiso | KANSL2 | KAP1 | KAT13A |
| KAT13D | KAT2A | KAT2B | KAT4 |
| KAT5 | KAT6A | KAT6B | KAT7 |
| KAT8 | KAT9 | ||
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