| Cat.No.: | PE-1279 |
| Product Name: | Recombinant Human CTSL1, GST-tagged |
| Product Overview: | Recombinant Human CTSL1 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
| Description: | The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. Multiple alternatively spliced transcript variants have been found for this gene. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Species: | Human |
| Tag: | GST |
| Expression System: | E. coli |
| Protein Length: | 1-333a.a. |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene Name: | CTSL1 cathepsin L1 [ Homo sapiens ] |
| Gene ID NCBI: | 1514 |
| Synonyms: | CTSL1; cathepsin L1; cathepsin L , CTSL; FLJ31037; cathepsin L; major excreted protein; MEP; CATL; CTSL; |
| mRNA Refseq: | NM_001257971 |
| Protein Refseq: | NP_001244900 |
| MIM: | 116880 |
| UniProt ID: | P07711 |
| Chromosome Location: | 9q21.33 |
| Function: | cysteine-type endopeptidase activity; cysteine-type endopeptidase activity; cysteine-type peptidase activity; histone binding; peptidase activity; protein binding; |
| Product Types | ||
| ◆ Cell Lines | ||
| CL-0168 | Human CTDSP1 Knockout Cell Line 26bp deletion | Inquiry |
| CL-0195 | Human CTDSPL Knockout Cell Line 1bp insertion | Inquiry |
| ◆ Extracts & Lysates | ||
| EL-0169 | Recombinant Human CTSL1 Cell Lysate | Inquiry |
| EL-0204 | Recombinant Human CTCFL 293 Cell Lysate | Inquiry |
| ◆ Antibodies | ||
| EAb-0849 | CTCF Polyclonal Antibody | Inquiry |
| Related Gene / Proteins | |||
| CTBP | CTBP2 | CTCF | CTCFL |
| CTDSP1 | CTDSPL | CtIP | ctnnb1 |
| CTSL1 | |||
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