| Cat.No.: | PE-1216 |
| Product Name: | Recombinant Human ARID4A, His-tagged |
| Product Overview: | AT-rich interactive domain-containing protein 4A (ARID4A), partial |
| Description: | The protein encoded by this gene is a ubiquitously expressed nuclear protein. It binds directly, with several other proteins, to retinoblastoma protein (pRB) which regulates cell proliferation. pRB represses transcription by recruiting the encoded protein. This protein, in turn, serves as a bridging molecule to recruit HDACs and, in addition, provides a second HDAC-independent repression function. The encoded protein possesses transcriptional repression activity. Multiple alternatively spliced transcripts have been observed for this gene, although not all transcript variants have been fully described. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Purity: | >90% |
| Species: | Human |
| Tag: | His |
| Expression System: | E. Coli or Yeast |
| Protein Length: | 1257 |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene Name: | ARID4A AT rich interactive domain 4A (RBP1-like) [ Homo sapiens ] |
| Gene ID NCBI: | 5926 |
| Synonyms: | ARID4A; AT rich interactive domain 4A (RBP1-like); RBBP1, retinoblastoma binding protein 1; AT-rich interactive domain-containing protein 4A; RBP 1; RBP1; retinoblastoma binding protein 1; retinoblastoma-binding protein 1; ARID domain-containing protein 4A; RBBP1; RBP-1; RBBP-1; |
| mRNA Refseq: | NM_002892 |
| Protein Refseq: | NP_002883 |
| MIM: | 180201 |
| UniProt ID: | P29374 |
| Chromosome Location: | 14q22.3 |
| Function: | DNA binding; sequence-specific DNA binding transcription factor activity; |
| Product Types | ||
| ◆ Cell Lines | ||
| CL-0001 | Human ARHGEF1 Knockout Cell Line 8bp deletion | Inquiry |
| CL-0002 | Human ARHGEF15 Knockout Cell Line | Inquiry |
| CL-0003 | Human ARHGEF11 Knockout Cell Line | Inquiry |
| CL-0004 | Human ARHGEF10L Knockout Cell Line | Inquiry |
| CL-0005 | Human ARHGEF12 Knockout Cell Line | Inquiry |
| Related Gene / Proteins | |||
| ARD1A | ARF1 | ARHGEF1 | ARHGEF10 |
| ARHGEF10L | ARHGEF11 | ARHGEF12 | ARHGEF15 |
| ARHGEF16 | ARHGEF17 | ARHGEF18 | ARHGEF19 |
| ARID1A | ARID1B | ARID2 | ARID3A |
| ARID4A | ARID5A | ARID5B | ARIH2 More > |
| AROS | ARTD10 | ||
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