| Cat.No.: | PE-1172 |
| Product Name: | Recombinant Human TBL1XR1 Protein, His-tagged |
| Product Overview: | Recombinant Human TBL1XR1 fused with His tag at N-terminal was expressed in E. coli. |
| Description: | This gene is a member of the WD40 repeat-containing gene family and shares sequence similarity with transducin (beta)-like 1X-linked (TBL1X). The protein encoded by this gene is thought to be a component of both nuclear receptor corepressor (N-CoR) and histone deacetylase 3 (HDAC 3) complexes, and is required for transcriptional activation by a variety of transcription factors. Mutations in these gene have been associated with some autism spectrum disorders, and one finding suggests that haploinsufficiency of this gene may be a cause of intellectual disability with dysmorphism. Mutations in this gene as well as recurrent translocations involving this gene have also been observed in some tumors. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Molecular Weight: | 55.4 kDa |
| Purity: | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Species: | Human |
| Formulation: | 25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1 % Sarkosyl. |
| Tag: | His |
| Expression System: | E. coli |
| Concentrations: | >50 ug/mL as determined by microplate BCA method |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene Name: | TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 [ Homo sapiens ] |
| Gene ID NCBI: | 79718 |
| Official Symbol: | TBL1XR1 |
| Synonyms: | TBL1XR1; transducin (beta)-like 1 X-linked receptor 1; transducin (beta) like 1X linked receptor 1; F-box-like/WD repeat-containing protein TBL1XR1; C21; DC42; FLJ12894; IRA1; TBLR1; TBL1-related protein 1; transducin beta-like 1X-related protein 1; nuclear receptor co-repressor/HDAC3 complex subunit; nuclear receptor corepressor/HDAC3 complex subunit TBLR1; |
| mRNA Refseq: | NM_024665 |
| Protein Refseq: | NP_078941 |
| MIM: | 608628 |
| UniProt ID: | Q9BZK7 |
| Product Types | ||
| ◆ Bioactive Small Molecules | ||
| BSM-0015 | Hesperadin | Inquiry |
| ◆ Proteins & Enzymes | ||
| PE-1170 | Recombinant Chicken TBL1XR1 | Inquiry |
| PE-1171 | Recombinant Mouse TBL1XR1 Protein | Inquiry |
| PE-1172 | Recombinant Human TBL1XR1 Protein, His-tagged | Inquiry |
| ◆ Antibodies | ||
| EAb-2567 | KAT4/TBP Associated Factor 1 Polyclonal Antibody | Inquiry |
| Related Gene / Proteins | |||
| TbAUK1 | TBL1XR1 | TBP | |
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