| Cat.No.: | PE-1152 |
| Product Name: | Recombinant Human PRKAA2/PRKAB2/PRKAG1, His-tagged |
| Product Overview: | Recombinant human PRKAA2 (amino acid residues 2-552), with N-terminal 6His, PRKAB2 (amino acid residues 1-272), PRKAG1 (amino acid residues 1-331) was expressed in E.coli. |
| Description: | Cloning of human 5"-AMP-activated protein kinase subunits alpha, beta and gamma (AMPKαβγ) was first described by Stapleton et al. (1996; 1997). AMPK is a highly conserved heterotrimeric enzyme consisting of three subunits, α, β, and γ, with multiple genes encoding distinct subunit isoforms (ie, α1, α2, β1, β2, γ1, γ2, and γ3) (Zungu et al., 2011). |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Molecular Weight: | AMPKA2 ~63.2 kDa; AMPKB2 ~30.3 kDa; AMPKG1 ~37.6 kDa |
| Species: | Human |
| Formulation: | 50 mM Tris/HCl pH7.5, 0.1 mM EGTA, 150 mM NaCl, 0.1% Mercaptoethanol, 270 mM sucrose, 0.03% Brij-35, 1 mM Benzamidine, 0.2 mM PMSF. |
| Tag: | His |
| Activity: | 4435 Units/mg (1198 Units/ml) Substrate: AMARA peptide (AMARAASAAALARRR) |
| Expression System: | E. coli |
| Concentrations: | 0.27 mg/ml |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene Name: | PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit [ Homo sapiens ] |
| Gene ID NCBI: | 5563 |
| Synonyms: | PRKAA2; protein kinase, AMP-activated, alpha 2 catalytic subunit; PRKAA; 5-AMP-activated protein kinase catalytic subunit alpha-2; AMPK; AMPKa2; AMPK-alpha-2 chain; AMPK subunit alpha-2; 5-AMP-activated protein kinase, catalytic alpha-2 chain; AMPK2; |
| mRNA Refseq: | NM_006252 |
| Protein Refseq: | NP_006243 |
| MIM: | 600497 |
| UniProt ID: | P54646 |
| Chromosome Location: | 1p31 |
| Function: | AMP-activated protein kinase activity; AMP-activated protein kinase activity; ATP binding; chromatin binding; histone serine kinase activity; metal ion binding; nucleotide binding; protein binding; protein binding, bridging; protein kinase activity; protein serine/threonine kinase activity; |
| Product Types | ||
| ◆ Bioactive Small Molecules | ||
| BSM-0027 | UNC0321 (trifluoroacetate salt) | Inquiry |
| BSM-0047 | SGC707 | Inquiry |
| ◆ Antibodies | ||
| EAb-0048 | PRMT6 Polyclonal Antibody | Inquiry |
| EAb-0049 | PRMT7 Polyclonal Antibody | Inquiry |
| EAb-0050 | PRMT1 Polyclonal Antibody | Inquiry |
| Related Gene / Proteins | |||
| Pr-SET7 | PRC1 | PRC2 | PRDM1 |
| PRDM10 | PRDM11 | PRDM12 | PRDM13 |
| PRDM14 | PRDM15 | PRDM16 | PRDM17 |
| PRDM2 | PRDM3 | PRDM4 | PRDM5 |
| PRDM6 | PRDM7 | PRDM8 | PRDM9 More > |
| PREP1 | PRIM2 | PRKAA2 | PRKCA |
| PRKCB | PRKCE | PRKDC | PRKRIP1 |
| PRMT | prmt1 | PRMT2 | PRMT3 |
| PRMT5 | prmt6 | PRMT7 | PRMT8 |
| PRMT9 | Progerin | Protamine 2 | Prox1 |
| PRPF31 | PRPF40A | PRSS12 | PRSS55 |
| PRTFDC1 | |||
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