| Cat.No.: | PE-1060 |
| Product Name: | Recombinant Mouse Protein Arginine N-methyltransferase 1, His-MBP-tagged |
| Product Overview: | Recombinant mousePRMT1, fused to His-MBP tag at N-terminus, was expressed in E. coli andpurified by using conventional chromatography techniques. |
| Description: | Protein arginineN-methyltransferase 1 (PRMT1) is a type I methyltransferase that transfers amethyl group from S-adenosylmethionine to guanidino nitrogens of arginineresidues to form monomethylarginine and asymmetric dimethylarginine.Functions of type I arginine methylation in proteins may include regulationof transcription, modulation of the affinity of nucleic acid-bindingproteins, regulation of interferon signaling pathways, and targeting ofnuclear proteins. Mouse PRMT1 shares 99.9% sequence identity with the humanproteins. |
| Applications: | SDS-PAGE |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Molecular Weight: | 84 kDa (750 aa) |
| Purity: | > 90% pure bySDS-PAGE |
| Species: | Mouse |
| Formulation: | Supplied as a liquidin 40 mM Tris, pH 8.0, containing 100 mM NaCl, 4 mM MgCl2, 2 mM DTT, and 40%glycerol. |
| Tag: | His-MBP |
| Amino Acid Sequence: | MHHHHHHMKI EEGKLVIWIN GDKGYNGLAE VGKKFEKDTG IKVTVEHPDK LEEKFPQVAA TGDGPDIIFWAHDRFGGYAQ SGLLAEITPD KAFQDKLYPF TWDAVRYNGK LIAYPIAVEA LSLIYNKDLL PNPPKTWEEIPALDKELKAK GKSALMFNLQ EPYFTWPLIA ADGGYAFKYE NGKYDIKDVG VDNAGAKAGL TFLVDLIKNKHMNAD |
| Expression System: | E. coli |
| Protein Length: | 11-353 |
| Concentrations: | 1 mg/ml |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene Name: | Prmt1protein arginine N-methyltransferase 1 [ Mus musculus ] |
| Gene ID NCBI: | 15469 |
| Synonyms: | Prmt1; proteinarginine N-methyltransferase 1; Mrmt1; Hrmt1l2; AW214366;6720434D09Rik; OTTMUSP00000022387; OTTMUSP00000022390; OTTMUSP00000022391;OTTMUSP00000022392; arginine N-methyltransferase 1; histone-arginineN-methyltransferase PRMT1; heterogeneous nuclear ribonucleoproteinsmethyltransferase-like 2; EC 2.1.1.125 |
| mRNA Refseq: | NM_019830 |
| Protein Refseq: | NP_062804 |
| UniProt ID: | Q9JIF0 |
| Chromosome Location: | 7 B4; 7 23.1 cM |
| Function: | protein binding;methyltransferase activity; histone-arginine N-methyltransferase activity;histone methyltransferase activity (H4-R3 specific); histonemethyltransferase activity; enzyme binding; core promoter proximal region DNAbinding; [cytochrome c]-arginine N-methyltransferase activity;N-methyltransferase activity; protein methyltransferase activity;protein-arginine omega-N asymmetric methyltransferase activity; snoRNPbinding; transferase activity |
| Product Types | ||
| ◆ Bioactive Small Molecules | ||
| BSM-0027 | UNC0321 (trifluoroacetate salt) | Inquiry |
| BSM-0047 | SGC707 | Inquiry |
| ◆ Antibodies | ||
| EAb-0048 | PRMT6 Polyclonal Antibody | Inquiry |
| EAb-0049 | PRMT7 Polyclonal Antibody | Inquiry |
| EAb-0050 | PRMT1 Polyclonal Antibody | Inquiry |
| Related Gene / Proteins | |||
| Pr-SET7 | PRC1 | PRC2 | PRDM1 |
| PRDM10 | PRDM11 | PRDM12 | PRDM13 |
| PRDM14 | PRDM15 | PRDM16 | PRDM17 |
| PRDM2 | PRDM3 | PRDM4 | PRDM5 |
| PRDM6 | PRDM7 | PRDM8 | PRDM9 More > |
| PREP1 | PRIM2 | PRKAA2 | PRKCA |
| PRKCB | PRKCE | PRKDC | PRKRIP1 |
| PRMT | prmt1 | PRMT2 | PRMT3 |
| PRMT5 | prmt6 | PRMT7 | PRMT8 |
| PRMT9 | Progerin | Protamine 2 | Prox1 |
| PRPF31 | PRPF40A | PRSS12 | PRSS55 |
| PRTFDC1 | |||
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