| Cat.No.: | PE-1046 |
| Product Name: | Recombinant Human CARM1, Flag-tagged |
| Product Overview: | Recombinant Human EZH2(amino-acids 2-end), fused with N-terminal Flag tag, was expressed in a FreeStyle 293-F cells. |
| Description: | This gene belongs to the protein arginine methyltransferase (PRMT) family. The encoded enzyme catalyzes the methylation of guanidino nitrogens of arginyl residues of proteins. The enzyme acts specifically on histones and other chromatin-associated proteins and is involved in regulation of gene expression. The enzyme may act in association with other proteins or within multi-protein complexes and may play a role in cell type-specific functions and cell lineage specification. A related pseudogene is located on chromosome 9. |
| Applications: | Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Molecular Weight: | 66 kDa |
| Purity: | Purity>70% |
| Species: | Human |
| Formulation: | 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 80 ug/ml Flag peptide, 20% glycerol and 3 mM DTT. |
| Tag: | Flag |
| Expression System: | Sf9 Insect Cells |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene Name: | CARM1 coactivator-associated arginine methyltransferase 1 [ Homo sapiens (human) ] |
| Gene ID NCBI: | 10498 |
| Synonyms: | CARM1; coactivator-associated arginine methyltransferase 1; PRMT4; EC 2.1.1.125; 3` partial; protein arginine N-methyltransferase 4; Histone-arginine methyltransferase CARM1; EC 2.1.1.-; Protein arginine N-methyltransferase 4; Coactivator-associated arginine methyltransferase 1 |
| mRNA Refseq: | NM_199141 |
| Protein Refseq: | NP_954592 |
| MIM: | 603934 |
| Chromosome Location: | 19p13.2 |
| Function: | histone methyltransferase activity (H3-R17 specific); histone-arginine N-methyltransferase activity; protein homodimerization activity |
| Product Types | ||
| ◆ Synthetic Peptides | ||
| SP-0008 | PRMT4 peptide substrate, Biotin-labeled | Inquiry |
| ◆ Cell Lines | ||
| CL-0050 | Human CARM1 Knockout Cell Line 8bp deletion | Inquiry |
| ◆ Bioactive Small Molecules | ||
| BSM-0123 | Ellagic acid | Inquiry |
| ◆ Extracts & Lysates | ||
| EL-0134 | Recombinant Human CARM1 293 Cell Lysate | Inquiry |
| EL-0148 | Recombinant Human CAMTA2 293 Cell Lysate | Inquiry |
| Related Gene / Proteins | |||
| CABIN1 | CAF1 | CAMKIV | CAMTA2 |
| CAPNS2 | CARHSP1 | CARM1 | CASC3 |
| CASP | CASP1 | CASP3 | |
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