| Cat.No.: | PE-1044 |
| Product Name: | Recombinant Human CARM1 |
| Product Overview: | Recombinant Human PRMT4, amino-acids 2-end expressed in a FreeStyle 293-F cells expression system. MW= 66 kDa. |
| Description: | CARM1 (coactivator-associated arginine methyltransferase 1) is an enzyme encoded by the CARM1 gene found in human beings, as well as many other mammals. CARM1 is a secondary coactivator through its association with p160 family (SRC-1, GRIP1, AIB) of coactivators. It is responsible for moving cells toward the inner cell mass in developing blastocysts. This gene also plays an important role in androgen receptors and may play a role in prostate cancer progression. |
| Applications: | Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Purity: | >60%. |
| Species: | Human |
| Formulation: | 25 mM Tris-HCl, pH 8.0, 100 mM NaCl, 0.05% Tween-20, 50% glycerol, and 3 mM DTT. |
| Expression System: | 293-F Cells |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene Name: | CARM1 coactivator-associated arginine methyltransferase 1 [ Homo sapiens ] |
| Gene ID NCBI: | 10498 |
| Synonyms: | CARM1; coactivator-associated arginine methyltransferase 1; PRMT4; EC 2.1.1.125; protein arginine N-methyltransferase 4; Histone-arginine methyltransferase CARM1; Protein arginine N-methyltransferase 4; Coactivator-associated arginine methyltransferase 1 |
| mRNA Refseq: | NM_199141 |
| Protein Refseq: | NP_954592 |
| MIM: | 603934 |
| UniProt ID: | Q86X55 |
| Chromosome Location: | 19p13.2 |
| Function: | histone-arginine N-methyltransferase activity; transferase activity; protein binding; transcription coactivator activity; protein methyltransferase activity |
| Product Types | ||
| ◆ Synthetic Peptides | ||
| SP-0008 | PRMT4 peptide substrate, Biotin-labeled | Inquiry |
| ◆ Cell Lines | ||
| CL-0050 | Human CARM1 Knockout Cell Line 8bp deletion | Inquiry |
| ◆ Bioactive Small Molecules | ||
| BSM-0123 | Ellagic acid | Inquiry |
| ◆ Extracts & Lysates | ||
| EL-0134 | Recombinant Human CARM1 293 Cell Lysate | Inquiry |
| EL-0148 | Recombinant Human CAMTA2 293 Cell Lysate | Inquiry |
| Related Gene / Proteins | |||
| CABIN1 | CAF1 | CAMKIV | CAMTA2 |
| CAPNS2 | CARHSP1 | CARM1 | CASC3 |
| CASP | CASP1 | CASP3 | |
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