| Cat.No.: | PE-1023 |
| Product Name: | Recombinant Human Ankyrin Repeat Domain 1 (Cardiac Muscle), His-tagged |
| Product Overview: | Recombinant human ANKRD1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. MW: 38.6 kDa. |
| Description: | Ankyrin repeat domain-containing protein 1, also known as ANKRD1, may play an important role in endothelial cell activation. This protein may act as a nuclear transcription factor that negatively regulates the expression of cardiac genes. |
| Applications: | SDS-PAGE |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Molecular Weight: | 38.6 kDa (342aa) confirmed by MALDI-TOF |
| Purity: | >85% by SDS - PAGE |
| Species: | Human |
| Formulation: | Liquid. In 20mM Tris-HCl buffer (pH 8.5) containing 0.2M NaCl, 50% glycerol, 5mM DTT |
| Tag: | His |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMMVLKVE ELVTGKKNGN GEAGEFLPED FRDGEYEAAV TLEKQEDLKT LLAHPVTLGE QQWKSEKQRE AELKKKKLEQ RSKLENLEDL EIIIQLKKRK KYRKTKVPVV KEPEPEIITE PVDVPTFLKA ALENKLPVVE KFLSDKNNPD VCDEYKRTAL HRACLEGHLA IVEKLMEAGA QIEFRDMLES TAIHWASRGG NLDVLKLLLN KGAKISARDK LLSTALHVAV RTGHYECAEH LIACEADLNA KDREGDTPLH DAVRLNRYKM IRLLIMYGAD LNIKNCAGKT PMDLVLHWQN GTKAIFDSLR ENSYKTSRIA TF |
| Expression System: | E. coli |
| Protein Length: | 1-319aa |
| Concentrations: | 0.25 mg/ml (determined by Bradford assay) |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene Name: | ANKRD1 ankyrin repeat domain 1 (cardiac muscle) [ Homo sapiens ] |
| Gene ID NCBI: | 27063 |
| Synonyms: | ANKRD1; ankyrin repeat domain 1 (cardiac muscle); ankyrin repeat domain-containing protein 1; ALRP; C 193; CARP; CVARP; MCARP; liver ankyrin repeat domain 1; cardiac ankyrin repeat protein; cytokine-inducible nuclear protein; cytokine-inducible gene C-193 protein; C-193; bA320F15.2; |
| mRNA Refseq: | NM_014391 |
| Protein Refseq: | NP_055206 |
| MIM: | 609599 |
| UniProt ID: | Q15327 |
| Chromosome Location: | 10q23.33 |
| Function: | DNA binding; R-SMAD binding; RNA polymerase II transcription coactivator activity; RNA polymerase II transcription factor binding; histone deacetylase binding; p53 binding; protein binding; titin binding; transcription corepressor activity; |
| Product Types | ||
| ◆ Antibodies | ||
| EAb-0057 | Phospho-ANAPC1 (Ser688) Polyclonal Antibody | Inquiry |
| ◆ Extracts & Lysates | ||
| EL-0131 | Recombinant Human ANKRD1 293 Cell Lysate | Inquiry |
| EL-0228 | Recombinant Human ANKRA2 293 Cell Lysate | Inquiry |
| ◆ Proteins & Enzymes | ||
| PE-1023 | Recombinant Human Ankyrin Repeat Domain 1 (Cardiac Muscle), His-tagged | Inquiry |
| PE-1024 | Recombinant Human ANKRD1, GST-tagged | Inquiry |
| Related Gene / Proteins | |||
| ANAPC1 | Androgen Receptor | ANKRA2 | ANKRD1 |
| ANKRD17 | ANO9A | ||
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