| Cat.No.: | PE-0989 |
| Product Name: | Recombinant Human SMYD1, FLAG-tagged |
| Product Overview: | Recombinant Human Smyd1 (accession number NP_938015.1) was expressed in Sf9 cells and contains an N-terminal FLAG tag with an observed molecular weight of 58.3 kDa. |
| Description: | SET and MYND domain-containing protein 1 (Smyd1) is a member of the Smyd family of histone methyltransferases that possesses H3K4 methyltransferase activity. It has also been shown to act as a transcriptional repressor. Studies suggest that Smyd1 may play a critical role in cardiomyocyte differentiation and cardiac morphogenesis and that it also may have a function in skeletal muscle development. |
| Applications: | Enzyme kinetics, inhibitor screening, and selectivity profiling. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Species: | Human |
| Formulation: | 20 mM Tris-HCl pH 7.4, 150 mM NaCl and 20% glycerol. |
| Tag: | FLAG |
| Activity: | Not known. May methylate non-histone substrates. |
| Expression System: | Sf9 Insect Cells |
| Concentrations: | 0.4 mg/ml |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene Name: | SMYD1 SET and MYND domain containing 1 [ Homo sapiens ] |
| Gene ID NCBI: | 150572 |
| Synonyms: | SMYD1; SET and MYND domain containing 1; SET and MYND domain-containing protein 1; BOP; KMT3D; ZMYND22; CD8 beta opposite; zinc finger, MYND domain containing 18; ZMYND18; |
| mRNA Refseq: | NM_198274 |
| Protein Refseq: | NP_938015 |
| MIM: | 606846 |
| UniProt ID: | Q8NB12 |
| Chromosome Location: | 2p11.1 |
| Function: | DNA binding; metal ion binding; transcription corepressor activity; zinc ion binding; |
| Product Types | ||
| ◆ Antibodies | ||
| EAb-0019 | SMARCA4 Polyclonal Antibody | Inquiry |
| ◆ Extracts & Lysates | ||
| EL-0063 | Recombinant Human SMARCC2 293 Cell Lysate | Inquiry |
| EL-0064 | Recombinant Human SMARCB1 Cell Lysate | Inquiry |
| ◆ Bioactive Small Molecules | ||
| BSM-0080 | AZ-505 ditrifluoroacetate | Inquiry |
| ◆ Research Kits | ||
| EKIT-0120 | BRG1 bromodomain TR-FRET Assay Kit | Inquiry |
| Related Gene / Proteins | |||
| SMAD3 | SMAD4 | SMARCA1 | SMARCA2 |
| SMARCA4 | SMARCA5 | SMARCA6 | SMARCAD1 |
| SMARCAL1 | SMARCB1 | SMARCC1 | SMARCC2 |
| SMARCD1 | SMARCD2 | SMARCD3 | SMARCE1 |
| SMC1-α | SMC3 | SMC4 | SMCHD1 More > |
| SMCX | SMN | SMN1 | SMN2 |
| SMOC2 | SMRT | SMT3 | SMUG1 |
| SMURF2 | SMYD1 | SMYD2 | SMYD2B |
| SMYD3 | SMYD4 | SMYD5 | |
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