| Cat.No.: | PE-0974 |
| Product Name: | Recombinant Human EHMT2, GST-tagged |
| Product Overview: | Recombinant Human G9a (euchromatic histone-lysine N-methyltransferase 2) (amino-acids 785-1210), with N-terminal GST tag expressed in E.Coli expression system. MW = 74.6 kDa. |
| Description: | Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 is an enzyme that in humans is encoded by the EHMT2 gene. A cluster of genes, BAT1-BAT5, has been localized in the vicinity of the genes for TNF alpha and TNF beta. This gene is found near this cluster; it was mapped near the gene for C2 within a 120-kb region that included a HSP70 gene pair. |
| Applications: | Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Purity: | >70%. |
| Species: | Human |
| Formulation: | 25 mM Tris-HCl, pH 8.0, 100 mM NaCl, 0.05% Tween-20, 30% glycerol, and 3 mM DTT. |
| Tag: | GST |
| Expression System: | E. coli |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene Name: | EHMT2 euchromatic histone-lysine N-methyltransferase 2 [ Homo sapiens ] |
| Gene ID NCBI: | 10919 |
| Synonyms: | EHMT2; euchromatic histone-lysine N-methyltransferase 2; G9A; BAT8; NG36; KMT1C; C6orf30; FLJ35547; DKFZp686H08213; G9A histone methyltransferase; H3-K9-HMTase 3; HLA-B associated transcript 8; ankyrin repeat-containing protein; histone H3-K9 methyltransferase 3; lysine N-methyltransferase 1C; protein G9a; EC 2.1.1.43 |
| mRNA Refseq: | NM_006709 |
| Protein Refseq: | NP_006700 |
| MIM: | 604599 |
| UniProt ID: | Q96KQ7 |
| Chromosome Location: | 6p21.31 |
| Function: | histone-lysine N-methyltransferase activity; metal ion binding; methyltransferase activity; protein binding; transferase activity; zinc ion binding |
| Product Types | ||
| ◆ Bioactive Small Molecules | ||
| BSM-0025 | BIX01294 (hydrochloride hydrate) | Inquiry |
| BSM-0026 | UNC0224 | Inquiry |
| BSM-0027 | UNC0321 (trifluoroacetate salt) | Inquiry |
| ◆ Cell Lines | ||
| CL-0059 | Human EHMT1 Knockout Cell Line 7bp deletion | Inquiry |
| CL-0060 | Human EHMT2 Knockout Cell Line 34bp deletion | Inquiry |
| Related Gene / Proteins | |||
| EHD2 | EHMT1 | EHMT2 | |
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