| Cat.No.: | PE-0934 |
| Product Name: | Recombinant Human TRNA Aspartic Acid Methyltransferase 1, His-tagged |
| Product Overview: | Recombinant humanTRDMT1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventionalchromatography. |
| Description: | TRDMT1 also known asDNMT2, specificallymethylates cytosine 38 in the anticodon loop of tRNA (Asp). |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Molecular Weight: | 47.2 kDa (415aa)confirmed by MALDI-TOF |
| Purity: | > 90% by SDS-PAGE |
| Species: | Human |
| Formulation: | Liquid. 20mMTris-HCl buffer (pH8.0) containing 20% glycerol, 0.1M NaCl, 1mM DTT. |
| Tag: | His |
| Amino Acid Sequence: | MGSSHHHHHHSSGLVPRGSH MGSHMEPLRV LELYSGVGGM HHALRESCIP AQVVAAIDVN TVANEVYKYNFPHTQLLAKT IEGITLEEFD RLSFDMILMS PPCQPFTRIG RQGDMTDSRT NSFLYILDIL PRLQKLPKYILLENVKGFEV SSTRDLLIQT IENCGFQYQE FLLSPTSLGI PNSRLRYFLI AKLQSEPLPF QAPGQVLMEFPKIESVHPQK YAMDVENKIQ EKNVEPNISF DGSIQCSGKD AILFKLETAE EIHRKNQQDS DLSVKMLKDFLEDDTDVNQY LLPPKSLLRY ALLLDIVQPT CRRSVCFTKG YGSYIEGTGS VLQTAEDVQV ENIYKSLTNLSQEEQITKLL ILKLRYFTPK EIANLLGFPP EFGFPEKITV KQRYRLLGNS LNVHVVAKLI KILYE |
| Expression System: | E. coli |
| Concentrations: | 1 mg/ml(determined by Bradford assay) |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene Name: | TRDMT1 tRNA aspartic acidmethyltransferase 1 [ Homo sapiens ] |
| Gene ID NCBI: | 1787 |
| Synonyms: | TRDMT1; tRNAaspartic acid methyltransferase 1; DMNT2; DNMT2; PuMet; RNMT1; M.HsaIIP; DNAmethyltransferase-2; DNA MTase homolog HsaIIP; DNA methyltransferase homologHsaIIP; DNA (cytosine-5-)-methyltransferase 2; EC 2.1.1.29; DNA(cytosine-5)-methyltransferase-like protein; MHSAIIP; PUMET; OTTHUMP00000019228;tRNA (cytosine(38)-C(5))-methyltransferase; tRNA(cytosine-5-)-methyltransferase; EC 2.1.1 |
| mRNA Refseq: | NM_004412 |
| Protein Refseq: | NP_004403 |
| MIM: | 602478 |
| UniProt ID: | O14717 |
| Chromosome Location: | 10p15.5 |
| Product Types | ||
| ◆ Bioactive Small Molecules | ||
| BSM-0018 | Danusertib (PHA-739358) | Inquiry |
| BSM-0021 | PF-03814735 | Inquiry |
| ◆ Extracts & Lysates | ||
| EL-0107 | Recombinant Human TRIM68 293 Cell Lysate | Inquiry |
| EL-0109 | Recombinant Human TRIP4 Lysate | Inquiry |
| EL-0115 | Recombinant Human TRIM24 293 Cell Lysate | Inquiry |
| Related Gene / Proteins | |||
| TRA2A | TRAF4 | TRAF5 | TRAF6 |
| TRAK2 | TRBP | TRDMT1 | TREX1 |
| TRF2 | TRIM11 | TRIM13 | TRIM16 |
| TRIM17 | TRIM2 | TRIM21 | trim24 |
| TRIM26 | TRIM28 | TRIM3 | TRIM33 More > |
| TRIM34 | TRIM35 | TRIM36 | TRIM37 |
| TRIM38 | TRIM39 | TRIM4 | TRIM5 |
| TRIM55 | TRIM6 | TRIM63 | TRIM66 |
| TRIM68 | TRIM8 | TRIM9 | TRIML1 |
| TRIP4 | Tristetraprolin | TRIT1 | TrkA |
| TRMT2A | TRMT44 | TRMT5 | TRMT6 |
| TROVE2 | TRUB2 | TRX1 | TRβ1 |
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