| Cat.No.: | PE-0933 |
| Product Name: | Recombinant Human TRDMT1 |
| Product Overview: | Recombinant full length Human Dnmt2 with N terminal proprietary tag, 69.08kDa. |
| Description: | This gene encodes a protein responsible for the methylation of aspartic acid transfer RNA, specifically at the cytosine-38 residue in the anticodon loop. This enzyme also possesses residual DNA-(cytosine-C5) methyltransferase activity. While similar in sequence and structure to DNA cytosine methyltransferases, this gene is distinct and highly conserved in its function among taxa. |
| Tissue Specificity: | Ubiquitous. Higher expression in testis, ovary and thymus and at much lower levels in spleen, prostate, colon, small intestine, and peripheral blood leukocytes. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Appearance: | Liquid |
| Molecular Weight: | 69.080kDa inclusive of tags |
| Species: | Human |
| Amino Acid Sequence: | MEPLRVLELYSGVGGMHHALRESCIPAQVVAAIDVNTVAN EVYKYNFPHTQLLAKTIEGITLEEFDRLSFDMILMSPPCQ PFTRIGRQGDMTDSRTNSFLYILDILPRLQKLPKYILLEN VKGFEVSSTRDLLIQTIENCGFQYQEFLLSPTSLGIPNSR LRYFLIAKLQSEPLPFQAPGQVLMEFPKIESVHPQKYAMD VENKIQEKNVEPNISFDGSIQCSGKDAILFKLETAEEIHR KNQQDSDLSVKMLKDFLEDDTDVNQYLLPPKSLLRYALLL DIVQPTCRRSVCFTKGYGSYIEGTGSVLQTAEDVQVENIY KSLTNLSQEEQITKLLILKLRYFTPKEIANLLGFPPEFGF PEKITVKQRYRLLGNSLNVHVVAKLIKILYE |
| Sequence Similarities: | Belongs to the C5-methyltransferase family. |
| Expression System: | Wheat germ |
| Protein Length: | 391 amino acids |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene Name: | TRDMT1 tRNA aspartic acid methyltransferase 1 [ Homo sapiens ] |
| Gene ID NCBI: | 1787 |
| Official Symbol: | TRDMT1 |
| Synonyms: | TRDMT1; tRNA aspartic acid methyltransferase 1; DNA (cytosine 5 ) methyltransferase 2 , DNMT2; tRNA (cytosine(38)-C(5))-methyltransferase; RNMT1; |
| mRNA Refseq: | NM_004412 |
| Protein Refseq: | NP_004403 |
| MIM: | 602478 |
| UniProt ID: | O14717 |
| Chromosome Location: | 10p15.1 |
| Function: | DNA (cytosine-5-)-methyltransferase activity; DNA binding; RNA binding; methyltransferase activity; transferase activity; |
| Product Types | ||
| ◆ Bioactive Small Molecules | ||
| BSM-0018 | Danusertib (PHA-739358) | Inquiry |
| BSM-0021 | PF-03814735 | Inquiry |
| ◆ Extracts & Lysates | ||
| EL-0107 | Recombinant Human TRIM68 293 Cell Lysate | Inquiry |
| EL-0109 | Recombinant Human TRIP4 Lysate | Inquiry |
| EL-0115 | Recombinant Human TRIM24 293 Cell Lysate | Inquiry |
| Related Gene / Proteins | |||
| TRA2A | TRAF4 | TRAF5 | TRAF6 |
| TRAK2 | TRBP | TRDMT1 | TREX1 |
| TRF2 | TRIM11 | TRIM13 | TRIM16 |
| TRIM17 | TRIM2 | TRIM21 | trim24 |
| TRIM26 | TRIM28 | TRIM3 | TRIM33 More > |
| TRIM34 | TRIM35 | TRIM36 | TRIM37 |
| TRIM38 | TRIM39 | TRIM4 | TRIM5 |
| TRIM55 | TRIM6 | TRIM63 | TRIM66 |
| TRIM68 | TRIM8 | TRIM9 | TRIML1 |
| TRIP4 | Tristetraprolin | TRIT1 | TrkA |
| TRMT2A | TRMT44 | TRMT5 | TRMT6 |
| TROVE2 | TRUB2 | TRX1 | TRβ1 |
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