| Cat.No.: | PE-0932 |
| Product Name: | Recombinant Human TRDMT1, His-tagged |
| Product Overview: | Recombinant Human TRDMT1 protein (Met 1-Glu 391), fused with the His tag at the N-terminus, was expressed in Insect cells. |
| Description: | TRDMT1, also known as tRNA (cytosine-5-)-methyltransferase, DNA methyltransferase homolog HsaIIP, and DNMT2, is a member of the DNA methyltransferase family of enzymes. While the role of other DNMT proteins has been extensively characterized, comparably little is known about DNMT2. It is the most widely conserved DNMT protein, with homologues in protists, plants, fungi, and animals. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Molecular Weight: | Predicts a molecular mass of 71 kDa. It migrates as an approximately 60 KDa band in SDS-PAGE under reducing conditions. |
| Purity: | > 94 % as determined by SDS-PAGE. |
| Species: | Human |
| Formulation: | Lyophilized from sterile 50Mm Tris ,100 mM Nacl , 0.5mM GSH, 0.5mM PMSF, pH 8.0. |
| Tag: | His |
| Endotoxin: | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Reconstitution: | A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information. |
| Expression System: | Insect Cells |
| Protein Length: | 616 amino acids |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene Name: | TRDMT1 tRNA aspartic acid methyltransferase 1 [ Homo sapiens ] |
| Gene ID NCBI: | 1787 |
| Synonyms: | TRDMT1; tRNA aspartic acid methyltransferase 1; DMNT2; DNMT2; PuMet; RNMT1; M.HsaIIP; DNA methyltransferase-2; DNA MTase homolog HsaIIP; DNA methyltransferase homolog HsaIIP; DNA (cytosine-5-)-methyltransferase 2; EC 2.1.1.29 |
| mRNA Refseq: | NM_004412 |
| Protein Refseq: | NP_004403 |
| MIM: | 602478 |
| UniProt ID: | O14717 |
| Chromosome Location: | 10p15.5 |
| Function: | DNA (cytosine-5-)-methyltransferase activity; RNA binding; methyltransferase activity; tRNA (cytosine-5-)-methyltransferase activity transferase activity; DNA binding |
| Product Types | ||
| ◆ Bioactive Small Molecules | ||
| BSM-0018 | Danusertib (PHA-739358) | Inquiry |
| BSM-0021 | PF-03814735 | Inquiry |
| ◆ Extracts & Lysates | ||
| EL-0107 | Recombinant Human TRIM68 293 Cell Lysate | Inquiry |
| EL-0109 | Recombinant Human TRIP4 Lysate | Inquiry |
| EL-0115 | Recombinant Human TRIM24 293 Cell Lysate | Inquiry |
| Related Gene / Proteins | |||
| TRA2A | TRAF4 | TRAF5 | TRAF6 |
| TRAK2 | TRBP | TRDMT1 | TREX1 |
| TRF2 | TRIM11 | TRIM13 | TRIM16 |
| TRIM17 | TRIM2 | TRIM21 | trim24 |
| TRIM26 | TRIM28 | TRIM3 | TRIM33 More > |
| TRIM34 | TRIM35 | TRIM36 | TRIM37 |
| TRIM38 | TRIM39 | TRIM4 | TRIM5 |
| TRIM55 | TRIM6 | TRIM63 | TRIM66 |
| TRIM68 | TRIM8 | TRIM9 | TRIML1 |
| TRIP4 | Tristetraprolin | TRIT1 | TrkA |
| TRMT2A | TRMT44 | TRMT5 | TRMT6 |
| TROVE2 | TRUB2 | TRX1 | TRβ1 |
USA
Enter your email here to subscribe.
Follow us on
Easy access to products and services you need from our library via powerful searching tools
