| Cat.No.: | PE-0884 |
| Product Name: | Recombinant Human KAT2A, His-tagged |
| Product Overview: | Recombinant human KAT2A protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques (411-837aa). |
| Description: | KAT2A, also known as GCN5L2(General control of amino acid synthesis protein 5 like 2), belongs to the GCN5 family. It functions as a histone acetyltransferase (HAT) to promote transcriptional activation. Acetylation of histones gives a specific tag for epigenetic transcription activation. GCN5L2 has been shown to interact with Ku70, TAF9, transcription initiation protein SPT3 homolog, TADA2L, Ku80 and DDB1. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Molecular Weight: | 51.1kDa (447aa), confirmed by MALDI-TOF |
| Purity: | > 90% by SDS - PAGE |
| Species: | Human |
| Formulation: | Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 5mM DTT, 40% glycerol, 200mM NaCl, 1mM EDTA |
| Tag: | His |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGGGSNSSLS LDSAGAEPMP GEKRTLPENL TLEDAKRLRV MGDIPMELVN EVMLTITDPA AMLGPETSLL SANAARDETA RLEERRGIIE FHVIGNSLTP KANRRVLLWL VGLQNVFSHQ LPRMPKEYIA RLVFDPKHKT LALIKDGRVI GGICFRMFPT QGFTEIVFCA VTSNEQVKGY GTHLMNHLKE YHIKHNILYF LTYADEYAIG YFKKQGFSKD IKVPKSRYLG YIKDYEGATL MECELNPRIP YTELSHIIKK QKEIIKKLIE RKQAQIRKVY PGLSCFKEGV RQIPVESVPG IRETGWKPLG KEKGKELKDP DQLYTTLKNL LAQIKSHPSA WPFMEPVKKS EAPDYYEVIR FPIDLKTMTE RLRSRYYVTR KLFVADLQRV IANCREYNPP DSEYCRCASA LEKFFYFKLK EGGLIDK |
| Expression System: | E. coli |
| Concentrations: | 0.25mg/ml (determined by Bradford assay) |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene Name: | KAT2A K(lysine) acetyltransferase 2A [ Homo sapiens ] |
| Gene ID NCBI: | 2648 |
| Official Symbol: | KAT2A |
| Synonyms: | KAT2A; K(lysine) acetyltransferase 2A; GCN5; hGCN5; GCN5L2; PCAF-b; MGC102791; histone acetyltransferase KAT2A; STAF97; hsGCN5; lysine acetyltransferase 2A; histone acetyltransferase GCN5; general control of amino acid synthesis protein 5-like 2; General control of amino acid synthesis, yeast, homolog-like 2; GCN5 (general control of amino-acid synthesis, yeast, homolog)-like 2; GCN5 general control of amino-acid synthesis 5-like 2 (yeast); Lysine acetyltransferase 2A; Histone acetyltransferase GCN5; EC 2.3.1.48 |
| mRNA Refseq: | NM_021078 |
| Protein Refseq: | NP_066564 |
| MIM: | 602301 |
| UniProt ID: | Q92830 |
| Chromosome Location: | 17q21 |
| Function: | histone acetyltransferase activity; N-acetyltransferase activity; histone deacetylase binding; protein binding; transcription coactivator activity; transferase activity |
| Product Types | ||
| ◆ Bioactive Small Molecules | ||
| BSM-0073 | Anacardic Acid | Inquiry |
| ◆ Antibodies | ||
| EAb-0073 | KAT8 Polyclonal Antibody | Inquiry |
| ◆ Cell Lines | ||
| CL-0083 | Human KAT2A Knockout Cell Line 1bp insertion | Inquiry |
| CL-0085 | Human KAT2B Knockout Cell Line 31bp deletion | Inquiry |
| ◆ Extracts & Lysates | ||
| EL-0159 | Recombinant Human MYST2 293 Cell Lysate | Inquiry |
| Related Gene / Proteins | |||
| Kaiso | KANSL2 | KAP1 | KAT13A |
| KAT13D | KAT2A | KAT2B | KAT4 |
| KAT5 | KAT6A | KAT6B | KAT7 |
| KAT8 | KAT9 | ||
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