| Cat.No.: | PE-0864 |
| Product Name: | Recombinant Human RELA protein, His & T7-tagged |
| Product Overview: | Recombinant Human RELA aa. (Pro19~Tyr306 (Accession # Q04206)) fused with N-terminal His & T7 tag was produced in E. coli cells. |
| Description: | NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene. |
| Applications: | SDS-PAGE; WB; ELISA; IP |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Appearance: | Freeze-dried powder |
| Molecular Weight: | Predicted Molecular Mass: 36.6kDa |
| Purity: | >95% |
| Species: | Human |
| Tag: | His & T7 |
| Endotoxin: | <1.0EU per 1µg (determined by the LAL method) |
| Reconstitution: | Reconstitute in sterile PBS, pH7.2-pH7.4. |
| Expression System: | E. coli |
| Isoelectric Point: | The isoelectric point is 8.8. |
| Protein Length: | Pro19~Tyr306 (Accession # Q04206) |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene Name: | RELA RELA proto-oncogene, NF-kB subunit [ Homo sapiens (human) ] |
| Gene ID NCBI: | 5970 |
| Official Symbol: | RELA |
| Synonyms: | RELA; RELA proto-oncogene, NF-kB subunit; p65; NFKB3; transcription factor p65; NF-kappa-B p65delta3; NF-kappa-B transcription factor p65; nuclear factor NF-kappa-B p65 subunit; nuclear factor of kappa light polypeptide gene enhancer in B-cells 3; v-rel avian reticuloendotheliosis viral oncogene homolog A; v-rel reticuloendotheliosis viral oncogene homolog A |
| mRNA Refseq: | NM_001145138.1 |
| Protein Refseq: | NP_001138610.1 |
| UniProt ID: | Q04206 |
| Product Types | ||
| ◆ Extracts & Lysates | ||
| EL-0113 | Recombinant Human RELA 293 Cell Lysate | Inquiry |
| ◆ Research Kits | ||
| EKIT-0275 | HEK 293 RELA Nuclear Translocation Assay Kit | Inquiry |
| ◆ Cell Lines | ||
| CL-0396 | Human RECQL4 Knockout Cell Line 5bp deletion | Inquiry |
| ◆ Proteins & Enzymes | ||
| PE-0856 | Recombinant Human RELA, His-tagged | Inquiry |
| PE-0857 | Recombinant Human RELA | Inquiry |
| Related Gene / Proteins | |||
| RECQL4 | rela | Reptin | REST |
| REXO5 | |||
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