| Cat.No.: | PE-0792 |
| Product Name: | Recombinant Human Protein Kinase C, Beta, GST-tagged, Active |
| Product Overview: | Recombinant human full-length PKCbeta I was expressed by baculovirus in Sf9 cells using an N-terminal GST tag. MW=102 kDa. |
| Description: | PKCβI is a member of the PKC family (phospholipid-dependent serine/threonine kinase) and is highly related to PKCβ II. Unlike the mature PKCβ II mRNA and protein, which rapidly increase following acute insulin treatment, the PKCβI mRNA and protein levels remain unchanged. The stable overexpression of PKCbetaII, but not PKCβI, leads to insulin-stimulated glucose uptake into cells. Upon stimulation of B lymphocytes and mast cells, Syk regulates Btk, and Btk selectively regulates enzymatic activity of PKCβI. Specific regulation of PKCβI by Btk is consistent with the selective association of Btk with PKCβI. |
| Applications: | Kinase Assay, Western Blot. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Species: | Human |
| Tag: | GST |
| Expression System: | Sf9 Insect Cells |
| Protein Length: | Full-length. |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene Name: | PRKCB protein kinase C, beta [ Homo sapiens ] |
| Gene ID NCBI: | 5579 |
| Synonyms: | PRKCB; protein kinase C, beta; PKCB; PRKCB1; PRKCB2; MGC41878; PKC-beta; Protein kinase C beta type; EC 2.7.11.13; PKC-B; protein kinase C, beta 1; protein kinase C, beta 1 polypeptide |
| mRNA Refseq: | NM_002738 |
| Protein Refseq: | NP_002729 |
| MIM: | 176970 |
| UniProt ID: | P05771 |
| Chromosome Location: | 16p12 |
| Function: | ATP binding; calcium ion binding; nucleotide binding; protein binding; protein kinase C activity; transferase activity; zinc ion binding |
| Product Types | ||
| ◆ Bioactive Small Molecules | ||
| BSM-0027 | UNC0321 (trifluoroacetate salt) | Inquiry |
| BSM-0047 | SGC707 | Inquiry |
| ◆ Antibodies | ||
| EAb-0048 | PRMT6 Polyclonal Antibody | Inquiry |
| EAb-0049 | PRMT7 Polyclonal Antibody | Inquiry |
| EAb-0050 | PRMT1 Polyclonal Antibody | Inquiry |
| Related Gene / Proteins | |||
| Pr-SET7 | PRC1 | PRC2 | PRDM1 |
| PRDM10 | PRDM11 | PRDM12 | PRDM13 |
| PRDM14 | PRDM15 | PRDM16 | PRDM17 |
| PRDM2 | PRDM3 | PRDM4 | PRDM5 |
| PRDM6 | PRDM7 | PRDM8 | PRDM9 More > |
| PREP1 | PRIM2 | PRKAA2 | PRKCA |
| PRKCB | PRKCE | PRKDC | PRKRIP1 |
| PRMT | prmt1 | PRMT2 | PRMT3 |
| PRMT5 | prmt6 | PRMT7 | PRMT8 |
| PRMT9 | Progerin | Protamine 2 | Prox1 |
| PRPF31 | PRPF40A | PRSS12 | PRSS55 |
| PRTFDC1 | |||
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