| Cat.No.: | PE-0737 |
| Product Name: | Recombinant Human SOD3 protein, His-tagged |
| Product Overview: | Recombinant Human SOD3(Trp19~Ala240) fused with His tag at N-terminal was expressed in E. coli. |
| Description: | This gene encodes a member of the superoxide dismutase (SOD) protein family. SODs are antioxidant enzymes that catalyze the conversion of superoxide radicals into hydrogen peroxide and oxygen, which may protect the brain, lungs, and other tissues from oxidative stress. Proteolytic processing of the encoded protein results in the formation of two distinct homotetramers that differ in their ability to interact with the extracellular matrix (ECM). Homotetramers consisting of the intact protein, or type C subunit, exhibit high affinity for heparin and are anchored to the ECM. Homotetramers consisting of a proteolytically cleaved form of the protein, or type A subunit, exhibit low affinity for heparin and do not interact with the ECM. A mutation in this gene may be associated with increased heart disease risk. |
| Applications: | SDS-PAGE; WB; ELISA; IP. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Molecular Weight: | 27.9 kDa |
| Purity: | > 95% |
| Species: | Human |
| Formulation: | PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300 |
| Tag: | His |
| Endotoxin: | <1.0EU per 1µg (determined by the LAL method) |
| Reconstitution: | Reconstitute in PBS or others. |
| Expression System: | E. coli |
| Protein Length: | Trp19~Ala240 |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene Name: | SOD3 superoxide dismutase 3, extracellular [ Homo sapiens ] |
| Gene ID NCBI: | 6649 |
| Official Symbol: | SOD3 |
| Synonyms: | SOD3; superoxide dismutase 3, extracellular; extracellular superoxide dismutase [Cu-Zn]; EC SOD; EC-SOD; MGC20077; |
| mRNA Refseq: | NM_003102 |
| Protein Refseq: | NP_003093 |
| MIM: | 185490 |
| UniProt ID: | P08294 |
| Chromosome Location: | 4pter-q21 |
| Function: | copper ion binding; heparin binding; metal ion binding; oxidoreductase activity; protein binding; superoxide dismutase activity; zinc ion binding; |
| Product Types | ||
| ◆ Extracts & Lysates | ||
| EL-0090 | Recombinant Human SOD3 293 Cell Lysate | Inquiry |
| ◆ Proteins & Enzymes | ||
| PE-0730 | Recombinant Human SOD3 | Inquiry |
| PE-0731 | Recombinant Human SOD3 | Inquiry |
| PE-0732 | Recombinant Human SOD3, GST-tagged | Inquiry |
| PE-0733 | Recombinant Mouse SOD3 Protein | Inquiry |
| Related Gene / Proteins | |||
| SOD1 | SOD2 | SOD3 | Sox11 |
| Sox2 | Sox6 | ||
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