| Cat.No.: | PE-0658 |
| Product Name: | Recombinant Human Protein Kinase N1, GST-tagged |
| Product Overview: | Recombinant humanfull length PKN1, GST-tagged. |
| Description: | PKN1 belongs to theprotein kinase C superfamily. This kinase is activated by the Rho family ofsmall G proteins and may mediate the Rho-dependent signaling pathway. This kinasecan also be activated by phospholipids. No special measures were taken toactivate this kinase. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Molecular Weight: | 132.1 kDa |
| Species: | Human |
| Formulation: | Liquid in 50 mMTris, pH 7.5 + 150 mM NaCl + 0.5 mM EDTA + 0.02% Triton X-100 + 2 mM DTT +50% glycerol |
| Tag: | GST |
| Expression System: | Insect Cells |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene Name: | PKN1 protein kinase N1 [ Homosapiens ] |
| Gene ID NCBI: | 5585 |
| Synonyms: | PKN1; protein kinaseN1; DBK; PKN; PAK1; PRK1; PAK-1; PRKCL1; MGC46204; PKN-ALPHA;serine/threonine-protein kinase N1; OTTHUMP00000037582; OTTHUMP00000037583;protein kinase C-like 1; protein kinase PKN-alpha; protein kinase C-like PKN;serine-threonine kinase N; protease-activated kinase 1; protein kinaseC-related kinase 1; protein-kinase C-related kinase 1; serine-threonineprotein kinase N; serine/threonine protein kinase N; EC 2.7.11.13 |
| mRNA Refseq: | NM_213560 |
| Protein Refseq: | NP_998725 |
| MIM: | 601032 |
| Chromosome Location: | 19p13.12 |
| Function: | ATP binding; GTP-Rhobinding; Rac GTPase binding; androgen receptor binding; chromatin binding;histone binding; histone deacetylase binding; histone kinase activity (H3-T11specific); ligand-dependent nuclear receptor transcription coactivatoractivity; nucleotide binding; protein binding; protein kinase C activity;protein kinase C binding; protein kinase activity; protein serine/threoninekinase activity |
| Product Types | ||
| ◆ Antibodies | ||
| EAb-0054 | PKC Polyclonal Antibody | Inquiry |
| EAb-0183 | PKM Polyclonal Antibody | Inquiry |
| ◆ Extracts & Lysates | ||
| EL-0078 | Recombinant Human PKN1 Cell Lysate | Inquiry |
| EL-0086 | Recombinant Human PKN2 293 Cell Lysate | Inquiry |
| ◆ Bioactive Small Molecules | ||
| BSM-0203 | Ro 31-8220 methanesulfonate | Inquiry |
| Related Gene / Proteins | |||
| PKC | PKM | PKM2 | PKN1 |
| PKN2 | |||
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