| Cat.No.: | PE-0565 |
| Product Name: | Recombinant Human SRF protein, His & T7-tagged |
| Product Overview: | Recombinant Human SRF aa. (Thr231~Gln474 (Accession # P11831)) fused with N-terminal His & T7 tag was produced in E. coli cells. |
| Description: | This gene encodes a ubiquitous nuclear protein that stimulates both cell proliferation and differentiation. It is a member of the MADS (MCM1, Agamous, Deficiens, and SRF) box superfamily of transcription factors. This protein binds to the serum response element (SRE) in the promoter region of target genes. This protein regulates the activity of many immediate-early genes, for example c-fos, and thereby participates in cell cycle regulation, apoptosis, cell growth, and cell differentiation. This gene is the downstream target of many pathways; for example, the mitogen-activated protein kinase pathway (MAPK) that acts through the ternary complex factors (TCFs). Two transcript variants encoding different isoforms have been found for this gene. |
| Applications: | SDS-PAGE; WB; ELISA; IP |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Appearance: | Freeze-dried powder |
| Molecular Weight: | Predicted Molecular Mass: 28.5kDa |
| Purity: | >95% |
| Species: | Human |
| Tag: | His & T7 |
| Endotoxin: | <1.0EU per 1µg (determined by the LAL method) |
| Reconstitution: | Reconstitute in sterile PBS, pH7.2-pH7.4. |
| Expression System: | E. coli |
| Isoelectric Point: | The isoelectric point is 5.9. |
| Protein Length: | Thr231~Gln474 (Accession # P11831) |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene Name: | SRF serum response factor [ Homo sapiens (human) ] |
| Gene ID NCBI: | 6722 |
| Official Symbol: | SRF |
| Synonyms: | MCM1; c-fos serum response element-binding transcription factor; minichromosome maintenance 1 homolog; serum response factor |
| mRNA Refseq: | NM_001292001.1 |
| Protein Refseq: | NP_001278930.1 |
| UniProt ID: | P11831 |
| Product Types | ||
| ◆ Research Kits | ||
| EKIT-0422 | SREBP-2 Transcription Factor Assay Kit | Inquiry |
| EKIT-0426 | SREBP-1 Transcription Factor Assay Kit | Inquiry |
| ◆ Proteins & Enzymes | ||
| PE-0560 | Recombinant Human SRF | Inquiry |
| PE-0561 | Recombinant Human SRF, His-tagged | Inquiry |
| PE-0562 | Recombinant Human SRF, His-tagged | Inquiry |
| Related Gene / Proteins | |||
| SRBD1 | SRC1 | SREBP | SREBP-1 |
| SREBP-2 | SRF | SRP14 | SRP19 |
| SRY | |||
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