| Cat.No.: | PE-0478 |
| Product Name: | Recombinant Human HDAC9 protein, His & T7-tagged |
| Product Overview: | Recombinant Human HDAC9 aa. (Pro23~Ala343 (Accession # Q9UKV0) fused with N-terminal His & T7 tag was produced in E. coli cells. |
| Description: | Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to the Xenopus and mouse MITR genes. The MITR protein lacks the histone deacetylase catalytic domain. It represses MEF2 activity through recruitment of multicomponent corepressor complexes that include CtBP and HDACs. This encoded protein may play a role in hematopoiesis. Multiple alternatively spliced transcripts have been described for this gene but the full-length nature of some of them has not been determined. |
| Applications: | SDS-PAGE; WB; ELISA; IP. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Appearance: | Freeze-dried powder |
| Molecular Weight: | Predicted Molecular Mass: 40.1kDa. |
| Purity: | >95% |
| Species: | Human |
| Tag: | His & T7 |
| Endotoxin: | <1.0EU per 1µg (determined by the LAL method) |
| Reconstitution: | Reconstitute in sterile PBS, pH7.2-pH7.4. |
| Expression System: | E. coli |
| Isoelectric Point: | The isoelectric point is 9.6. |
| Protein Length: | Pro23~Ala343 (Accession # Q9UKV0) |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene Name: | HDAC9 histone deacetylase 9 [ Homo sapiens (human) ] |
| Gene ID NCBI: | 9734 |
| Official Symbol: | HDAC9 |
| Synonyms: | HDAC9; histone deacetylase 9; HD7; HD9; HD7b; HDAC; HDRP; MITR; HDAC7; HDAC7B; HDAC9B; HDAC9FL; MEF-2 interacting transcription repressor (MITR) protein; histone deacetylase 4/5-related protein; histone deacetylase 7B |
| mRNA Refseq: | NM_001204144.2 |
| Protein Refseq: | NP_001191073.1 |
| UniProt ID: | Q9UKV0 |
| Product Types | ||
| ◆ Extracts & Lysates | ||
| EL-0006 | Recombinant Human HDAC1 293 Cell Lysate | Inquiry |
| EL-0007 | Recombinant Human HDAC2 293 Cell Lysate | Inquiry |
| EL-0008 | Recombinant Human HDAC3 Cell Lysate | Inquiry |
| EL-0009 | Recombinant Human HDAC4 Cell Lysate | Inquiry |
| ◆ Bioactive Small Molecules | ||
| BSM-0007 | Tubacin | Inquiry |
| Related Gene / Proteins | |||
| HDAC | HDAC1 | HDAC10 | HDAC11 |
| HDAC2 | HDAC3 | hdac4 | hdac5 |
| HDAC6 | hdac7 | HDAC8 | hdac9 |
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