| Cat.No.: | PE-0391 |
| Product Name: | Recombinant Human CITED2, His-tagged |
| Product Overview: | Recombinant full length Human CITED2 fused to His tag at C-terminal; amino acids 1-270 , 29.5kDa. |
| Description: | The protein encoded by this gene inhibits transactivation of HIF1A-induced genes by competing with binding of HIF1a to p300-CH1. Mutations in this gene are a cause of cardiac septal defects. Three transcript variants encoding the same protein have been found for this gene. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Appearance: | Liquid |
| Purity: | >90% by SDS-PAGE |
| Species: | Human |
| Tag: | His |
| Amino Acid Sequence: | MADHMMAMNH GRFPDGTNGL HHHPAHRMGM GQFPSPHHHQ QQQPQHAFNA LMGEHIHYGA GNMNATSGIR HAMGPGTVNG GHPPSALAPA ARFNNSQFMG PPVASQGGSL PASMQLQKLN NQYFNHHPYP HNHYMPDLHP AAGHQMNGTN QHFRDCNPKH SGGSSTPGGS GGSSTPGGSG SSSGGGAGSS NSGGGSGSGN MPASVAHVPA AMLPPNVIDT DFIDEEVLMS LVIEMGLDRI KELPELWLGQ NEFDFMTDFV CKQQPSRVSC LEHHHHHH |
| Sequence Similarities: | Belongs to the CITED family. |
| Expression System: | E. coli |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene Name: | CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 [ Homo sapiens ] |
| Gene ID NCBI: | 10370 |
| Official Symbol: | CITED2 |
| Synonyms: | CITED2; Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2; cbp/p300-interacting transactivator 2; MRG1; |
| mRNA Refseq: | NM_001168388 |
| Protein Refseq: | NP_001161860 |
| UniProt ID: | Q99967 |
| Chromosome Location: | 6q23.3 |
| Function: | LBD domain binding; chromatin binding; protein binding; sequence-specific DNA binding transcription factor activity; transcription coactivator activity; |
| Product Types | ||
| ◆ Extracts & Lysates | ||
| EL-0040 | Recombinant Human CITED2 Cell Lysate | Inquiry |
| EL-0114 | Recombinant Human CITED1 293 Cell Lysate | Inquiry |
| ◆ Cell Lines | ||
| CL-0387 | Human CIB1 Knockout Cell Line | Inquiry |
| ◆ Proteins & Enzymes | ||
| PE-0389 | Recombinant Human CITED2, His-tagged | Inquiry |
| PE-0390 | Recombinant Human CITED2, His-tagged | Inquiry |
| Related Gene / Proteins | |||
| CIB1 | CIRP | CITED1 | CITED2 |
| CIZ1 | |||
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