| Cat.No.: | PE-0337 |
| Product Name: | Recombinant Human BRD4, His-tagged |
| Product Overview: | Recombinant protein includes Bromo 2 domain (342-460 aa) with a N-terminal His-tag. |
| Description: | BrD4 protein is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. It plays a role in a process governing chromosomal dynamics during mitosis. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Appearance: | Liquid |
| Molecular Weight: | 12.4 kDa (106 aa, 342-460 aa +NT-His Tag) |
| Purity: | ≥98% by SDS-PAGE |
| Species: | Human |
| Formulation: | rh-BrD4 is supplied as a solution in 50 mM Tris, pH 8.0, 150 mM NaCl and 10% Glycerol. |
| Tag: | His |
| Expression System: | HEK293 |
| Protein Length: | 342-460 aa |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene Name: | BRD4 bromodomain containing 4 [ Homo sapiens (human) ] |
| Gene ID NCBI: | 23476 |
| Synonyms: | BRD4; bromodomain containing 4; CAP; MCAP; HUNK1; HUNKI; bromodomain-containing protein 4; bromodomain-containing 4; chromosome-associated protein; EC 3.1.1.31 |
| mRNA Refseq: | NM_014299 |
| Protein Refseq: | NP_055114 |
| MIM: | 608749 |
| UniProt ID: | O60885 |
| Chromosome Location: | 19p13.1 |
| Function: | DNA binding; protein binding |
| Product Types | ||
| ◆ Synthetic Peptides | ||
| SP-0001 | Bromodomain Non-Acetylated Ligand 4 | Inquiry |
| SP-0002 | Bromodomain Non-Acetylated Ligand 3 | Inquiry |
| SP-0003 | Bromodomain Non-Acetylated Ligand 1 | Inquiry |
| SP-0004 | Bromodomain Ligand 3 | Inquiry |
| SP-0006 | Bromodomain Ligand 4 | Inquiry |
| Related Gene / Proteins | |||
| BRCA1 | BRCA2 | BRCC3 | BRD |
| brd1 | brd2 | brd3 | brd4 |
| BRD7 | BRD8 | brd9 | brdt |
| BRL | BRM | BRMS1 | BRPF1 |
| BRPF2 | brpf3 | BRWD1 | BRWD3 |
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