| Cat.No.: | PE-0274 |
| Product Name: | Recombinant Human DNM3A protein, GST-tagged |
| Product Overview: | Recombinant Human DNMT3A protein, fused with N-terminal GST tag, was expressed in insect cell. |
| Description: | DNA (cytosine-5)-methyltransferase 3a (DNMT3a) is required for de novo DNA methylation and methylates at both CpG and non-CpG sites. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Molecular Weight: | 127.7 kDa |
| Purity: | >80% by SDS-PAGE |
| Species: | Human |
| Formulation: | 50 mM Tris/HCl pH 8.0, 125 mM NaCl, 3 mM DTT, 10% glycerol (v/v). |
| Tag: | GST |
| Expression System: | Insect Cells |
| Protein Length: | 2-912 |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene Name: | DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha [ Homo sapiens ] |
| Gene ID NCBI: | 1788 |
| Official Symbol: | DNMT3A |
| Synonyms: | DNMT3A; DNA (cytosine-5-)-methyltransferase 3 alpha; DNA (cytosine-5)-methyltransferase 3A; DNA MTase HsaIIIA; DNA cytosine methyltransferase 3A2; DNMT3A2; M.HsaIIIA; |
| mRNA Refseq: | NM_022552 |
| Protein Refseq: | NP_072046 |
| MIM: | 602769 |
| UniProt ID: | Q9Y6K1 |
| Chromosome Location: | 2p23 |
| Function: | DNA (cytosine-5-)-methyltransferase activity; DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates; DNA binding; chromatin binding; metal ion binding; methyltransferase activity; protein binding; transferase activity; unmethylated CpG bi |
| Product Types | ||
| ◆ Bioactive Small Molecules | ||
| BSM-0008 | Vinorelbine Tartrate | Inquiry |
| ◆ Extracts & Lysates | ||
| EL-0027 | Recombinant Human DNMT3A 293 Cell Lysate | Inquiry |
| EL-0028 | Recombinant Human DNMT3B 293 Cell Lysate | Inquiry |
| EL-0029 | Recombinant Human DNMT3L 293 Cell Lysate | Inquiry |
| EL-0030 | Recombinant Human DNMT3L 293 Cell Lysate | Inquiry |
| Related Gene / Proteins | |||
| DNA alkyltransferase | DNAJC2 | DNAS1L1 | DNASE1L3 |
| DNMT | DNMT1 | DNMT2 | DNMT3A |
| DNMT3B | DNMT3L | DNMT4 | |
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