| Cat.No.: | PE-0116 |
| Product Name: | Recombinant Human Histone Deacetylase 11, GST-tagged |
| Product Overview: | Recombinant full length human HDAC11 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. |
| Description: | HDAC11 belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. HDAC11 belongs to class IV of the histone deacetylase family that localizes to the nucleus and is involved in regulating the expression of interleukin 10. HDAC11 expression is the highest in brain, heart, skeletal muscle, kidney and testis. |
| Applications: | HDAC Assay, Western Blot |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Molecular Weight: | 66 kDa |
| Purity: | >75% |
| Species: | Human |
| Formulation: | Recombinant protein stored in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol. |
| Tag: | GST |
| Activity: | 52 RLU/min/ng |
| Expression System: | Sf9 Insect Cells |
| Protein Length: | Full length |
| Concentrations: | 0.1 ug/ul |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene Name: | HDAC11 histone deacetylase 11 [ Homo sapiens ] |
| Gene ID NCBI: | 79885 |
| Official Symbol: | HDAC11 |
| Synonyms: | HDAC11; histone deacetylase 11; HD11; FLJ22237; histone deacetylase 11; OTTHUMP00000160231; OTTHUMP00000197639; OTTHUMP00000197644; OTTHUMP00000197649; OTTHUMP00000208001; OTTHUMP00000209466; OTTHUMP00000226982 |
| mRNA Refseq: | NM_024827 |
| Protein Refseq: | NP_079103 |
| MIM: | 601241 |
| UniProt ID: | Q96DB2 |
| Chromosome Location: | 3p25 |
| Function: | NAD-dependent histone deacetylase activity (H3-K14 specific); NAD-dependent histone deacetylase activity (H3-K9 specific); NAD-dependent histone deacetylase activity (H4-K16 specific); histone deacetylase activity; histone deacetylase activity (H3-K16 specific); hydrolase activity; transcription factor binding |
| Product Types | ||
| ◆ Extracts & Lysates | ||
| EL-0006 | Recombinant Human HDAC1 293 Cell Lysate | Inquiry |
| EL-0007 | Recombinant Human HDAC2 293 Cell Lysate | Inquiry |
| EL-0008 | Recombinant Human HDAC3 Cell Lysate | Inquiry |
| EL-0009 | Recombinant Human HDAC4 Cell Lysate | Inquiry |
| ◆ Bioactive Small Molecules | ||
| BSM-0007 | Tubacin | Inquiry |
| Related Gene / Proteins | |||
| HDAC | HDAC1 | HDAC10 | HDAC11 |
| HDAC2 | HDAC3 | hdac4 | hdac5 |
| HDAC6 | hdac7 | HDAC8 | hdac9 |
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