| Cat.No.: | PE-0087 |
| Product Name: | Recombinant Human Histone Deacetylase 7, GST-tagged |
| Product Overview: | Full Length Human HDAC7–Class IIa, 107kD with GST tag. |
| Description: | Histone deacetylase 7, also known as HDAC7, is a human gene. Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via transcriptional corepressor SMRT. Multiple alternatively spliced transcript variants encoding several isoforms have been found for this gene. |
| Storage: | Store at 4℃ if entire vial will be used within 2-4 weeks. Store at -20℃ or -80℃ for longer periods of time. Avoid multiple freeze-thaw cycles. |
| Species: | Human |
| Purification: | Ni2+ Affinity Column |
| Formulation: | 25mM Tris pH8, 120mM NaCl, 0.05% Tween-20 & 40% Glycerol. |
| Tag: | GST |
| Activity: | 1000 units per vial. 1 unit is defined as the amount of enzyme that will convert 1picomole per minute per ug of protein at pH8 at 30℃. |
| Expression System: | Baculovirus-Insect Cells |
| Warning: | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene Name: | HDAC7 histone deacetylase 7 [ Homo sapiens ] |
| Gene ID NCBI: | 51564 |
| Synonyms: | HDAC7A; HDAC7; DKFZP586J0917; histone deacetylase 7; FLJ99588; histone deacetylase 7A. |
| mRNA Refseq: | NM_015401 |
| Protein Refseq: | NP_056216 |
| MIM: | 606542 |
| UniProt ID: | Q8WUI4 |
| Chromosome Location: | 12q13.1 |
| Function: | histone deacetylase activity; hydrolase activity |
| Product Types | ||
| ◆ Extracts & Lysates | ||
| EL-0006 | Recombinant Human HDAC1 293 Cell Lysate | Inquiry |
| EL-0007 | Recombinant Human HDAC2 293 Cell Lysate | Inquiry |
| EL-0008 | Recombinant Human HDAC3 Cell Lysate | Inquiry |
| EL-0009 | Recombinant Human HDAC4 Cell Lysate | Inquiry |
| ◆ Bioactive Small Molecules | ||
| BSM-0007 | Tubacin | Inquiry |
| Related Gene / Proteins | |||
| HDAC | HDAC1 | HDAC10 | HDAC11 |
| HDAC2 | HDAC3 | hdac4 | hdac5 |
| HDAC6 | hdac7 | HDAC8 | hdac9 |
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