CHD4 Monoclonal Antibody


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Cat.No.:  EAb-3487
Product Name:  CHD4 Monoclonal Antibody
Antibody Type:  Monoclonal
Immunogen:  Recombinant protein of human CHD4
Host:  Mouse
Isotype:  IgG
Molecular Weight:  300kDa
Purification:  Affinity purification
Appearance:  Liquid
Applications:  WB
Recommended Dilutions/Conditions:  WB: 1:500 - 1:1000
Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user.
Positive Control:  293T,HL-60,Jurkat,K-562,A375,LO2
Species Reactivity:  Human
Storage:  -20℃.
Storage Buffer:  PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Warning:  For Research Use Only! Not For Use in Humans.
Accession:  Swiss Prot Q14839; Gene ID 1108
Alternative Name:  CHD4; CHD-4; Mi-2b; Mi2-BETA; SIHIWES; chromodomain-helicase-DNA-binding protein 4
Scientific Background:  The product of this gene belongs to the SNF2/RAD54 helicase family. It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression. Patients with dermatomyositis develop antibodies against this protein. Somatic mutations in this gene are associated with serous endometrial tumors. Alternative splicing results in multiple transcript variants encoding different isoforms.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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