Cat.No.: | EAb-3455 |
Product Name: | SMARCE1 Polyclonal Antibody |
Antibody Type: | Polyclonal |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-411 of human SMARCE1 |
Immunogen Sequence: | MSKRPSYAPPPTPAPATQMPSTPGFVGYNPYSHLAYNNYRLGGNPGTNSRVTASSGITIPKPPKPPDKPLMPYMRYSRKVWDQVKASNPDLKLWEIGKIIGGMWRDLTDEEKQEYLNEYEAEKIEYNESMKAYHNSPAYLAYINAKSRAEAALEEESRQRQSRMEKGEPYMSIQPAEDPDDYDDGFSMKHTATARFQRNHRLISEILSESVVPDVRSVVTTARMQVLKRQVQSLMVHQRKLEAELLQIEERHQEKKRKFLESTDSFNNELKRLCGLKVEVDMEKIAAEIAQAEEQARKRQEEREKEAAEQAERSQSSIVPEEEQAANKGEEKKDDENIPMETEETHLEETTESQQNGEEGTSTPEDKESGQEGVDSMAEEGTSDSNTGSESNSATVEEPPTDPIPEDEKKE |
Host: | Rabbit |
Isotype: | IgG |
Molecular Weight: | 55kDa |
Purification: | Affinity purification |
Appearance: | Liquid |
Applications: | WB; IHC; IF |
Recommended Dilutions/Conditions: |
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200 Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
Positive Control: | U-251MG,Jurkat |
Species Reactivity: | Human, Mouse |
Storage: | -20℃. |
Storage Buffer: | PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
Warning: | For Research Use Only! Not For Use in Humans. |
Accession: | Swiss Prot Q969G3; NP_003070.3; Gene ID 6605 |
Alternative Name: | SMARCE1; BAF57; CSS5; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 |
Scientific Background: | The protein encoded by this gene is part of the large ATP-dependent chromatin remodeling complex SWI/SNF, which is required for transcriptional activation of genes normally repressed by chromatin. The encoded protein, either alone or when in the SWI/SNF complex, can bind to 4-way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome. The protein contains a DNA-binding HMG domain, but disruption of this domain does not abolish the DNA-binding or nucleosome-displacement activities of the SWI/SNF complex. Unlike most of the SWI/SNF complex proteins, this protein has no yeast counterpart. |
Product Types | ||
◆ Antibodies | ||
EAb-0019 | SMARCA4 Polyclonal Antibody | Inquiry |
◆ Extracts & Lysates | ||
EL-0063 | Recombinant Human SMARCC2 293 Cell Lysate | Inquiry |
EL-0064 | Recombinant Human SMARCB1 Cell Lysate | Inquiry |
◆ Bioactive Small Molecules | ||
BSM-0080 | AZ-505 ditrifluoroacetate | Inquiry |
◆ Research Kits | ||
EKIT-0120 | BRG1 bromodomain TR-FRET Assay Kit | Inquiry |
Related Gene / Proteins | |||
SMAD3 | SMAD4 | SMARCA1 | SMARCA2 |
SMARCA4 | SMARCA5 | SMARCA6 | SMARCAD1 |
SMARCAL1 | SMARCB1 | SMARCC1 | SMARCC2 |
SMARCD1 | SMARCD2 | SMARCD3 | SMARCE1 |
SMC1-α | SMC3 | SMC4 | SMCHD1 More > |
SMCX | SMN | SMN1 | SMN2 |
SMOC2 | SMRT | SMT3 | SMUG1 |
SMURF2 | SMYD1 | SMYD2 | SMYD2B |
SMYD3 | SMYD4 | SMYD5 |
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