| Cat.No.: | EAb-3453 |
| Product Name: | EED Polyclonal Antibody |
| Antibody Type: | Polyclonal |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human EED |
| Immunogen Sequence: | MSEREVSTAPAGTDMPAAKKQKLSSDENSNPDLSGDENDDAVSIESGTNTERPDTPTNTPNAPGRKSWGKGKWKSKKCKYSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNRVTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPNKTNRPFISQKIHFPDFS |
| Host: | Rabbit |
| Isotype: | IgG |
| Molecular Weight: | 50kDa |
| Purification: | Affinity purification |
| Appearance: | Liquid |
| Applications: | WB |
| Recommended Dilutions/Conditions: |
WB: 1:500 - 1:2000 Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user. |
| Positive Control: | Mouse heart |
| Species Reactivity: | Human, Mouse, Rat |
| Storage: | -20℃. |
| Storage Buffer: | PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
| Warning: | For Research Use Only! Not For Use in Humans. |
| Accession: | Swiss Prot O75530; NP_694536.1; Gene ID 8726 |
| Alternative Name: | EED; HEED; WAIT1; polycomb protein EED |
| Scientific Background: | This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein interacts with enhancer of zeste 2, the cytoplasmic tail of integrin beta7, immunodeficiency virus type 1 (HIV-1) MA protein, and histone deacetylase proteins. This protein mediates repression of gene activity through histone deacetylation, and may act as a specific regulator of integrin function. Two transcript variants encoding distinct isoforms have been identified for this gene. |
| Product Types | ||
| ◆ Extracts & Lysates | ||
| EL-0026 | Recombinant Human EED Cell Lysate | Inquiry |
| ◆ Bioactive Small Molecules | ||
| BSM-0166 | MAK-683 | Inquiry |
| ◆ Research Kits | ||
| EKIT-0182 | EZH2-EED Binding Assay Kit | Inquiry |
| ◆ Antibodies | ||
| EAb-0196 | EEF1A Polyclonal Antibody | Inquiry |
| ◆ Proteins & Enzymes | ||
| PE-0248 | Recombinant Human EED, His & GST tagged | Inquiry |
| Related Gene / Proteins | |||
| EED | EEF1A1 | EEF1A2 | EEF1B2 |
| EEF1G | |||
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