RBBP7 Polyclonal Antibody


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Cat.No.:  EAb-3441
Product Name:  RBBP7 Polyclonal Antibody
Antibody Type:  Polyclonal
Immunogen:  A synthetic peptide of human RBBP7
Host:  Rabbit
Isotype:  IgG
Molecular Weight:  55kDa
Purification:  Affinity purification
Appearance:  Liquid
Applications:  WB; FC
Recommended Dilutions/Conditions:  WB: 1:500 - 1:1000
Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user.
Positive Control:  HeLa
Species Reactivity:  Human
Storage:  4℃.
Storage Buffer:  PBS with 0.02% sodium azide, pH7.3.
Warning:  For Research Use Only! Not For Use in Humans.
Accession:  Swiss Prot Q16576; Gene ID 5931
Alternative Name:  RBBP7; RbAp46; histone-binding protein RBBP7
Scientific Background:  This protein is a ubiquitously expressed nuclear protein and belongs to a highly conserved subfamily of WD-repeat proteins. It is found among several proteins that binds directly to retinoblastoma protein, which regulates cell proliferation. The encoded protein is found in many histone deacetylase complexes, including mSin3 co-repressor complex. It is also present in protein complexes involved in chromatin assembly. This protein can interact with BRCA1 tumor-suppressor gene and may have a role in the regulation of cell proliferation and differentiation. Two transcript variants encoding different isoforms have been found for this gene.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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