HMGB2 Polyclonal Antibody


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Cat.No.:  EAb-3403
Product Name:  HMGB2 Polyclonal Antibody
Antibody Type:  Polyclonal
Immunogen:  Recombinant protein of human HMGB2.
Host:  Rabbit
Isotype:  IgG
Molecular Weight:  30kDa
Purification:  Affinity purification
Appearance:  Liquid
Applications:  WB; IHC; IF
Recommended Dilutions/Conditions:  WB: 1:500 - 1:2000; IHC: 1:50 - 1:100
Recommended dilutions/conditions may not be available for all applications. Specific conditions for reactivity should be optimized by the end user.
Positive Control:  HeLa,293T,U-87MG,RAW264.7,PC-12
Species Reactivity:  Human, Mouse, Rat
Storage:  -20℃.
Storage Buffer:  PBS with 0.02% sodium azide, pH7.3.
Warning:  For Research Use Only! Not For Use in Humans.
Accession:  Swiss Prot P26583; Gene ID 3148
Alternative Name:  HMGB2; HMG2; high mobility group box 2
Scientific Background:  This gene encodes a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination.

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For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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